安体舒通治疗慢性充血性心力衰竭的疗效观察  

Efficacy of Spironolactone Treatment of Chronic Congestive Heart Failure

作　　者：刘蓉昕[1] 

机构地区：[1]吉林省人民医院循环科,吉林长春130021

出　　处：《中国医药指南》2013年第16期62-63,共2页Guide of China Medicine

摘　　要：目的对安体舒通治疗慢性充血性心力衰竭(CHF)在临床中的疗效进行观察。方法对我院2010年2月至2012年10月收治的慢性充血性心力衰竭患者121例,随机分为对照组和观察组组。对照组60例,观察组61例。对照组采用常规心力衰竭治疗法,观察组则在常规治疗慢性充血性心力衰竭的基础上,每天一次加服20mg的安体舒通片,两组均进行4周的治疗。两组通过治疗前后,对利用动态心电图监测到的心律失常情况和左心功能进行对比。结果观察组与对照组比较,观察组的各项指标明显优于对照组,心功能得到有效改善(P<0.05);室性心律失常发生率减少(P<0.01)。结论安体舒通片对改善慢性充血性心力衰竭患者的心功能疗效良好,降低了室性心律失常的发生率,有推广意义。Objective Spironolactone on the treatment of chronic congestive heart failure （CHF） in the clinical curative effect observation. Methods The clinical data from February 2010 to October 2012 patients of chronic congestive heart failure patients 121 cases were randomly divided into control group and observation way. Sixty cases of control group and observation group 61 examples. Control group with normal heart failure therapy, the observation group is in the conventional treatment of chronic congestive heart failure, on the basis of once a day and clothing and mg of spironolactone piece, two groups are on the four weeks of treatment. The two groups before and after treatment, the use of dynamic electrocardiogram （DCG） to arrhythmia and left cardiac function were compared. Results The observation group compared with controls, the indicators of the observation group was better than control group, and effectively improve cardiac function （P〈O.O1）; To reduce the incidence of ventricular arrhythmia （P〈O.O1）. Conclusion Spironolactone tablet to improve chronic congestive heart failure patients with cardiac function good curative effect and reduce the incidence of ventricular arrhythmia, promoting significance.

关 键 词：安体舒通片 充血性心力衰竭 疗效 

分 类 号：R541.6[医药卫生—心血管疾病]