酮咯酸氨丁三醇联合间苯三酚治疗急性痉挛性腹痛的临床疗效观察  

Curative effect of combination treatment by ketorolac tromethamine and phloroglucinol on the acute spasmodic abdominal pain

作　　者：郭聪芳[1] 

机构地区：[1]天津市第一中心医院急诊科,天津300192

出　　处：《现代医学》2013年第6期390-393,共4页Modern Medical Journal

摘　　要：目的:观察间苯三酚联合酮咯酸氨丁三醇治疗急性痉挛性腹痛患者的临床疗效。方法:将200例急性痉挛性腹痛患者随机分为4组:间苯三酚组(A组)、山莨菪碱组(B组)、酮咯酸氨丁三醇组(C组)和间苯三酚+酮咯酸氨丁三醇组(D组),分别对各组进行治疗前后疼痛程度评分,记录用药至疼痛缓解的最早起效时间、30 min的疼痛缓解率;观察各组患者面红、口干、心悸、视力模糊、恶心等不良反应发生率。结果:D组疼痛缓解的起效时间最短,30 min疼痛缓解率最高,与A、B、C组比较差异均有统计学意义。A组不良反应最少,B组不良反应最多,B组与C、D组比较差异有统计学意义。结论:间苯三酚联合酮咯酸氨丁三醇治疗急性痉挛性腹痛疗效较好。Objective： To observe the clinical effect of the combination of ketorolac tromethamine and phloroglucinol on the acute spasmodic abdominal pain.Methods： Two hundred patients with acute spasmodic abdominal pain were divided randomly into four groups： group A（treatment of phloroglucinol）,group B（treatment of anisodamine）,group C（treatment of ketorolac tromethamine） and group D（combination of ketorolac tromethamine and phloroglucinol）.The degrees of pain before and after the treatment were scored,the earliest time of pain relief and the pain relief rate in 30 min were recorded,the incidence of the adverse reaction such as the red face,dry mouth,palpitation,blurred vision,nausea were observed.Results： The time of pain relief was the earliest,and the pain relief rate in 30 min was the highest in Group D.Compared with group A,B,C,there were statistical differences.Group A had the minimum incidence of the adverse reaction.Group B had the maximum incidence of the adverse reaction,compared with group C,D,the differences were statistically significant.Conclusion： The combination of ketorolac tromethamine and phloroglucinol in the remission of acute spasmodic abdominal pain is the best.

关 键 词：间苯三酚 酮咯酸氨丁三醇 急性痉挛性腹痛 

分 类 号：R453.9[医药卫生—治疗学] R572[医药卫生—临床医学]