中医药抗肝纤维化的疗效观察  

Clinical observation on antifibrotic of TCM

作　　者：谢家能[1] 

机构地区：[1]广西灵山县人民医院,广西灵山535400

出　　处：《中医临床研究》2013年第13期10-11,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨中医药辨证治疗对肝纤维化患者的临床疗效,并进行分析。方法:选取2010年12月～2012年12月期间就诊于我院的肝纤维化患者120例进行回顾性分析并随机分为两组,每组60例。其中,对照组患者采用常规的西药治疗(本研究口服甘草酸二铵肠溶胶囊为主,150mg/次,3次/d);而观察组则在对照组的基础上自拟中药方剂辨证治疗。观察两组患者治疗前后肝纤维化标志物的变化情况,比较两种方法的临床疗效。结果:治疗后,观察组肝纤维化标志物的降低情况明显优于对照组;另外,观察组的总有效率为96.67%,而对照组的总有效率则为75.00%,观察组的疗效也明显高于对照组,经分析,各组差异均具有统计学意义(P<0.05)。结论:中医药辨证治疗具有逆转肝纤维化的作用,其疗效确切,安全性高,值得在临床上推广应用。Objective： To investigate the clinical efficacy of TCM for antifibrotic and analyze it. Methods： Retrospectively analyzed the 120 patients with liver fibrosis in our hospital from December 2010 to December 2012. Randomly divided into two groups and 60 cases in each group. The control group were treated with conventional modem medicine （In this study, oral the enteric-coated capsules of diammonium glycyrrhizinate, 150mg/time, 3 times/day）. While the observation group were treated in TCM on the basis of treatment of the control group. Before and after treatment, observed the liver fibrosis markers of the two groups and compared the clinical efficacy. Results; After treatment, the liver fibrosis markers of the observation group were reduced more than that of the control group. In addition, the total efficiency of the observation group was 96.67%, while the control group was 75.00%. Visible, the efficacy of the observation group was significantly higher than that of the control group, which had statistically significant differences （P〈0.05）, Conclusion： TCM intervention eould reverse liver fibrosis. It is effective and safe, worth clinical practice.

关 键 词：中医药 抗肝纤维化 辨证治疗 疗效 

分 类 号：R563[医药卫生—呼吸系统]