支原体与粘液脓性宫颈炎的相关性研究与药敏分析  

The correlation between mycoplasma infection and mucopurulent cervicitis and analysis of drug sensitivity

作　　者：李腾蛟 邱洁 肖锋 郭义龙 曾彩 

机构地区：[1]广东省汕头市皮肤性病防治院,广东汕头515041

出　　处：《皮肤病与性病》2013年第3期132-133,共2页Dermatology and Venereology

基　　金：汕头市皮肤性病防治院重点科技计划项目;项目编号:汕市财文[2010]480号

摘　　要：目的探讨支原体感染与粘液脓性宫颈炎的相关性并分析其临床药敏。方法将220例粘液脓性宫颈炎患者设为观察组、将222例宫颈无黏液脓性分泌物患者设为对照组,进行病原体检测并比较两者主要病原谱的异同;同时进行支原体药敏检测。结果观察组中病原菌检出率89.09%,单一病原体感染占66.82%(147/220),混合感染率22.27%(49/220),其中解脲支原体(UU)为35%(77/220)、淋球菌(NG)为33.18%(73/220)、沙眼衣原体(CT)为36.36%(80/220);两组比较经统计分析差异有统计学意义(P<0.01),提示解脲支原体同样是引起粘液脓性宫颈炎的主要病原体。而人型支原体(MH)检出率与对照组差异无统计学意义(P>0.05)。结论粘液脓性宫颈炎主要病原体为解脲支原体、淋球菌、沙眼衣原体。其中UU对罗红霉素、环丙沙星、乙酰螺旋霉素耐药率最高,左旋氧氟沙星、克拉霉素、阿奇霉素次之,美满霉素、交沙霉素、多西环素耐药率最低。Objective To discuss the correlation between mycoplasma infection and mucopurulent cervicitis and analyze its clinical drug sensitivity. Methods The major pathogens were detected and analyzed in 220 patients with mucopurulent cervicitis and 222 normal controls, and the drug sensitivity tests were performed for mycoplasma. Results The detection rate in case group was 89.09% , and the single infection was 66. 82% （147/220）. The mixing infection was 22. 27% （49/220）, in which urea plasma urealyticum infection was 35% （77/ 220）, neisseria gonorrhoeae infection was 33.18% （73/220） , and ehlamydia traehomatis infection was 36. 36% （80/220）. There was significant difference between case and control groups （ P〈0. 01 ）. There have no significant difference in positive rate of mycoplasma hominis between two groups（ P〉0. 05 ） , which suggest ureaplasma urealyticum was also the major pathogens of patients with mucopurulent cervicitis. Conclusion The major pathogens of mucopurulent cervicitis were ureaplasma urealyticum, neisseria gonorrhoeae and chlamydia trachomatis. The highest susceptible curative drugs to ureaplasma urealyticum were Minocycline, Josamyein and Doxycycline Levofolxacin, Clarithromycin and Azithromycin were middle sensitive, and Roxithromycin, Ciprofloxacin, Acetyl spiramycin has high resistance.

关 键 词：支原体 粘液脓性宫颈炎 药敏分析 

分 类 号：R446.62[医药卫生—诊断学] R711.32[医药卫生—临床医学]