轻度认知功能障碍与颈动脉狭窄的相关性研究  

Relationship between Carotid Artery Stenosis and Mild Cognitive Impairment

作　　者：梁金[1] 刘文博[1] 孙建平[1] 谷新医[1] 马强[1] 

机构地区：[1]大连大学附属中山医院神经内科,辽宁大连116001

出　　处：《医学与哲学（B）》2013年第6期49-51,共3页Medicine & Philosophy(B)

摘　　要：为了探讨颈动脉狭窄与轻度认知功能障碍(MCI)的关系,选取轻度认知功能障碍病例89例,健康对照组100例,全部行颈动脉彩超检查及简易智能状态量表(MMSE),蒙特利尔认知量表(MoCA),临床痴呆量表(CDR),日常生活能力量表(ADL),汉密尔顿抑郁量表(HAMD)测评。结果发现轻度认知功能障碍组颈动脉狭窄发生率明显高于对照组,左侧发生率明显高于右侧。其中随着狭窄的严重程度增加,患者在延迟回忆、视空间与执行功能、计算力与注意力、语言能力方面评分显著下降。从这一结果可以看出轻度认知功能障碍与颈动脉狭窄密切相关。To investigate the relationship between carotid artery stenosis and mild cognitive impairment, 89 elderly patients with mildly recognition disorder and elder healthy group were studied. All carotid artery were examined with color doppler ultrasound, the level of MMSE, MoCA, CDR, ADL, HAMD of the two groups were measured. Further comparison and correlative analysis were made. Compared with elder healthy group （100 controls）, carotid artery stenosis of the MCI group （89 cases） is more serious. The left carotid artery stenosis more serious than the other side. With the increase of ca- rotid artery stenosis, cognitive impairment aggravated gradually. The cognitive function decline accompanying the level of carotid artery stenosis in elderly.

关 键 词：颈动脉狭窄 认知障碍 蒙特利尔认知量表 

分 类 号：R543.2[医药卫生—心血管疾病]