健脾祛风方治疗特应性皮炎95例临床观察  

Clinical Effect of "Jianpi Qufeng Decoction" in Treating 95 Patients with Atopic Dermatitis

作　　者：彭勇[1] 李斌[2] 李锋[3] 王英杰[1] 武宗琴 柴维汉 

机构地区：[1]上海市嘉定区中医医院皮肤科,上海201800 [2]上海中医药大学附属岳阳中西医结合医院皮肤科,上海200437 [3]复旦大学附属华山医院皮肤科,上海200040

出　　处：《上海中医药大学学报》2013年第3期45-47,共3页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：上海市卫生局中医药科研基金资助项目(2010L081A)

摘　　要：目的:探讨健脾祛风方治疗脾虚型特应性皮炎的临床疗效及其对皮肤角质层含水量和pH值的影响。方法:将192例特应性皮炎患者随机分为治疗组(95例)和对照组(97例)。所有患者除给予尿素乳膏外用外,治疗组采用健脾祛风方口服,对照组采用西替利嗪口服,治疗疗程为4周。评价两组患者的临床疗效,检测治疗前后患者皮肤角质层含水量、皮肤pH值的变化。结果:治疗组的总有效率为82.11%,明显高于对照组的61.86%(P<0.05)。治疗后,两组患者的SCORAD积分较治疗前均显著降低(P<0.05),且治疗组的SCORAD积分明显低于对照组(P<0.05)。治疗后,两组患者的皮肤角质层含水量均显著增加(P<0.05),皮肤pH值显著降低(P<0.05);且治疗组患者的皮肤角质层含水量、皮肤pH值与对照组相比,差异亦有统计学意义(P<0.05)。结论:健脾祛风方治疗脾虚型特应性皮炎具有较好的疗效。Objective： To explore the therapeutic effect of ＂Jianpi Qufeng Decoction＂ for atopic dermatitis（AD） of spleen-deficiency syndrome,and its influence on skin hydration and pH.Methods： One hundred and ninety-two patients with AD were randomly divided into treatment group（95 cases） and control group（97 cases）.All the patients were treated with urea cream externally,besides the treatment group was treated with ＂Jianpi Qufeng Decoction＂ and the control group was treated with cetirizine,with a course of four weeks.The clinical effect was evaluated,and the skin hydration and pH were detected.Results： The total effective rates of treatment group and control group were 82.11% and 61.86% respectively,with statistical difference between two groups（P＆lt;0.05）.After treatment,the scores of SCORAD in both groups were significantly decreased（P＆lt;0.05）,and the scores of treatment group were lower than those of control group（P＆lt;0.05）.After treatment,the skin hydration was increased and the skin pH was decreased in both groups（P＆lt;0.05）,and there were statistical differences on skin hydration and pH between two groups（P＆lt;0.05）.Conclusion： ＂Jianpi Qufeng Decoction＂ has good effect on atopic dermatitis of spleen-deficiency type.

关 键 词：健脾祛风方 脾虚证 特应性皮炎 

分 类 号：R275[医药卫生—中医皮科]