参附汤结合常规疗法治疗慢性阻塞性肺疾病急性加重36例  

Combination of "Shenfu Decoction" and routine treatment for acute exacerbation of chronic obstructive pulmonary disease:a report of 36 cases

作　　者：陈晓晶[1] 武晨亮[1] 马效东[1] 

机构地区：[1]浙江省杭州市余杭区第三人民医院呼吸内科,浙江杭州311115

出　　处：《上海中医药杂志》2013年第6期52-53,共2页Shanghai Journal of Traditional Chinese Medicine

摘　　要：目的观察参附汤结合常规疗法治疗慢性阻塞性肺疾病急性加重的临床疗效。方法将72例慢性阻塞性肺病急性加重的机械通气患者随机分为治疗组和对照组,每组36例。两组均给予抗炎、祛痰、呼吸机辅助通气等常规治疗,治疗组在此基础上加用参附汤煎汤鼻饲。两组疗程均为12天,观察气管插管情况及血气分析指标变化情况。结果治疗组气管插管时间及二次插管病例数均少于对照组(P<0.05);治疗组治疗前后二氧化碳分压(PaCO2)、氧分压(PaO2)比较,差异有统计学意义(P<0.05);组间治疗后氧分压(PaO2)比较,差异有统计学意义(P<0.05)。结论参附汤结合常规疗法可明显改善慢性阻塞性肺病急性加重机械通气患者的通气与换气功能,缩短机械通气时间,改善预后。Objective To observe the clinical efficacy of ＂Shenfu Decoction＂ combined with routine treatment in treating acute exacerbation of chronic obstructive pulmonary disease（AE-COPD）.Methods Seventy-two mechanically ventilated patients with AE-COPD were randomly divided into treatment group and control group,36 in each group.The two groups were treated by anti-inflammatory,expectorant,mechanical ventilation and other routine treatment,and treatment group was additional treated by nasogastric ＂Shenfu Decoction＂,with the course of 12 days.The clinical efficacy was observed.Results After treatment,there was significant difference in intubation time and cases of secondary intubation between the two groups（P0.05）;there was significant difference in PaCO2 and PaO2 in treatment group between before and after treatment（P0.05）;significant difference was found in PaO2 between the two groups after treatment（P0.05）.Conclusion ＂Shenfu Decoction＂ can significantly improve ventilation function,shorten the duration of mechanical ventilation and improve the prognosis in patients with AE-COPD.

关 键 词：慢性阻塞性肺疾病 急性加重 参附汤 机械通气 

分 类 号：R563.9[医药卫生—呼吸系统]