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机构地区:[1]湖北省武汉亚洲心脏病医院心脏外科,430022
出 处:《中国综合临床》2013年第8期831-833,共3页Clinical Medicine of China
摘 要:目的观察动态血糖监测系统(CGMS)和胰岛素泵皮下输注系统(CSII)组成的双C方案在合并2型糖尿病(T2DM)的冠状动脉搭桥患者围手术期的临床疗效。方法将拟行冠状动脉搭桥手术的T2DM患者分为双C治疗组(双C组,n=20)和胰岛素多次皮下注射组(MSII组,n=30),观察两组患者术前、术后血糖的控制值、血糖的波动幅度、胰岛素的用量、血糖达标的时间、低血糖的发生率、切口感染率、总住院时间。结果双C组和MSII组血糖的波动幅度分别为(5.76±1.42)、(7.91±1.68)mmol/L(P〈0.05),胰岛素的用量分别为(38.82±16.97)、(49.00±15.32)U/d(P=0.032),血糖的达标时间分别为(3.52±1.13)、(6.00±4.27)d(P=0.002),发生低血糖分别为4例和1例(P=0.025),切口感染均为1例(P=0.948),总住院时间分别为(23.68±13.67)、(30.12±2.94)d(P=0.084)。结论采用双c方案对冠状动脉搭桥患者围术期的血糖控制更加全面和有效。Objective To observe the clinical efficacy of the double C program consisting of glucose monitoring systems ( CGMS ) and insulin pump ( CSII ) in perioperative period of patients undergoing coronary artery bypass patients with type2 diabetes mellitus ( T2DM ). Methods Divided participants who underwent coronary artery bypass surgery with T2DM into double C treatment group (double C group, n = 20) and multiple subcutaneous insulin group (MSII group,n = 30). Before and after surgery, blood sugar control in blood glucose time, blood sugar fluctuations, the amount of insulin, the incidence of low blood sugar, incision infection, and total hospitalization days were observed. Results Comparing the double C treatment group with the MSII group, blood sugar fluctuations ( ( 5.76 ± 1.42 ) mmol/L vs. ( 7.91 ± 1.68 ) mool/L, P 〈 0. 05 ), the amount of insulin ( (38. 82 ± 16. 97) U/d vs. ( 49. 00 ± 15.32 ) U/d, P = 0. 032 ), the blood sugar compliance time ( ( 3.52 ± 1.13 ) d vs. (6. 00 ± 4. 27 ) d, P = 0. 002), hypoglycemia ( 4 cases vs. 1 case, P = 0. 025 ), the incision infection rates in both the cases(P =0. 948) ,the total admission days( (23.68 ± 13.67) d vs. (30. 12 ± 2. 94) d,P = 0. 084). Conclusion The double C program is comprehensively effective, for the perioperative glycemic control of patients with T2DM undergoing coronary artery bypass.
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