缬沙坦治疗心血管疾病的临床疗效观察  

作　　者：程飞[1] 兰军[1] 涂昌[1] 陈本发[1] 蕫家龙 

机构地区：[1]南方医科大学附属东莞市石龙人民医院心血管内科,广东523326

出　　处：《当代医学》2013年第21期141-142,共2页Contemporary Medicine

摘　　要：目的探讨缬沙坦在治疗心血管疾病方面的临床疗效。方法选取2010年1月-2011年1月期间收治的心血管患者120例,随机分为观察组和对照组,对照组给予常规临床治疗,观察组在常规治疗基础上给予缬沙坦口服治疗,比较两组患者的临床疗效情况。结果两组患者舒张压、收缩压均明显下降,并均达到理想水平,两组患者的治疗后舒张压、收缩压之间也没有显著性差异,P>0.05。观察组治疗后随访,共发生心血管事件2例,发生率为3.33%;对照组治疗后随访,共发生心血管事件10例,发生率为16.67%。观察组的心血管事件发生率明显低于对照组,并具有显著性差异,(χ2=34.23,P<0.05),有统计学意义。结论心血管患者在常规治疗的基础上联合缬沙坦治疗,可以更好的舒张血管,提高对心血管的保护作用,进一步提高临床疗效,值得临床推广使用。Objective To investigate the clinical efficacy of Valsartan in treatment of cardiovascular diseases. Methods The hospital from January 2010 to January 2011 cardiovascular patients treated 120 cases were randomly divided into observation group and control group, the control group received routine clinical observation group was given Valsartan on the basis of conventional therapy oral treatment, the clinical efficacy of the two groups were compared. Results The two groups of patients with diastolic blood pressure, systolic blood pressure were significantly decreased, and to achieve the desired level of diastolic blood pressure in the two groups of patients after treatment, there was no significant difference between the systolic blood pressure （P〉0.05）. After treatment~ follow-up, two cases of cardiovascular events, incidence of 3.33%; control group after treatment follow-up, a total of 10 cases of cardiovascular events, the rate was 16.67%. Observation group, the incidence of cardiovascular events was significantly lower than the control group, with a significant difference （X^2= 34.23,P〈0.05） was statistically significant. Conclusion Patients with cardiovascular disease on the basis of conventional therapy combined with Valsartan in the treatment, can better relaxing blood vessels, improve the protective effect on cardiovascular system, further improve clinical efficacy, is worthy of clinical use.

关 键 词：缬沙坦 心血管疾病 临床疗效 

分 类 号：R54[医药卫生—心血管疾病]