姜黄素治疗代谢综合征的研究进展  

The Progress of Curcumin in Metabolic Syndrome

作　　者：邵琳琳[1] 戴雅玥[2] 冯文焕[3] 

机构地区：[1]南京中医药大学中西医结合鼓楼临床医学院,江苏南京210008 [2]东南大学医学院,江苏南京210009 [3]南京大学医学院附属鼓楼医院内分泌科,江苏南京210008

出　　处：《现代生物医学进展》2013年第20期3988-3992,共5页Progress in Modern Biomedicine

基　　金：江苏省自然基金项目(BK200861);南京市医学科技发展项目(YKK11092)

摘　　要：姜黄素是从姜黄中提取的一种多酚类物质,近年来对姜黄素的研究日趋广泛,已明确具有抗肿瘤,抗炎,抗氧化、降糖、降脂等多种药理作用,在临床上广泛应用于治疗肿瘤、肥胖、糖尿病等多种疾病。代谢综合征是一组以代谢紊乱为特征的症候群,包括中心性肥胖、糖脂代谢异常、高血压、非酒精性脂肪肝等,这些病理状态长期发展,可进一步导致心、脑血管患病率明显升高,研究发现姜黄素能够改善代谢综合征。现就近年来有关姜黄素治疗代谢综合征的研究进展综述如下。Curcumin, a polyphenolic substances extracted fi＇om turmeric, has anti-cancer, anti-inflammatory, antioxidant, hypoglycemic, lipid-lowering and other pharmacological effects, has been widely used in the clinical treatment of cancer, obesity, diabetes and other diseases. Metabolic syndrome is a group of metabolic disorders characterized syndrome, including central obesity, glucolipid metabolic abnormalities, high blood pressure, nonalcoholic fatty liver disease, the development of these pathological state can further lead to increased prevalence of heart and cerebrovascular diseases. Recent studies have found that curcumin can improve the metabolic syndrome. This article reviewed the progress of curcumin treatment of metabolic syndrome according to the lately researches.

关 键 词：姜黄素 代谢综合征 

分 类 号：R589[医药卫生—内分泌]