交联β-环糊精-可溶性淀粉聚合物的微球吸附防晒剂行为  

Preparation and Sunscreen Absorption Characterization of Crosslinked β-CD and Water-Soluble Starch Microspheres

作　　者：董伟 范旭 曹光群 

机构地区：[1]江南大学化学与材料工程学院

出　　处：《光谱实验室》2013年第4期1871-1875,共5页Chinese Journal of Spectroscopy Laboratory

摘　　要：以对甲氧基肉桂酸异辛酯(OMC)和交联β-环糊精-可溶性淀粉聚合物微球为原料,以OMC包封率和载料质量分数为评价指标,通过单因素设计对制备交联β-环糊精-可溶性淀粉聚合物微球吸附OMC的工艺条件进行了优化。结果表明:OMC:交联β-环糊精-可溶性淀粉聚合物微球=1∶100(质量比),50%乙醇溶液为溶剂,25℃下反应60min,包封率为63.63%,载料质量分数6.59%;在0—24h内,OMC在β-环糊精-可溶性淀粉聚合物微球中的累积释料率符合零级释放规律。Sunscreen absorption of crosslinked β-CD and water-soluble starch microspheres was prepared and characterized.Isooctyl p-methoxycinnamate（OMC） was used as model sunscreen.The absorption of OMC by microspheres was studied under different conditions（mass ratio of materials,temperature,time and particle size）.The optimization condition is as follows：the mass ratio of OMC and microspheres is 1∶100,reaction temperature is 25℃,reaction time is 60 min,entrapment efficiency and OMC loading are 63.63% and 6.59%,respectively.In release study,the release behavior of OMC in polymer microspheres was studied and there was almost no change in the release rate of OMC during 24hours.Crosslinked β-CD and water-soluble starch microspheres may be an ideal sunscreen release carrier.

关 键 词：交联β-环糊精-可溶性淀粉聚合物微球 对甲氧基肉桂酸异辛酯 防晒剂缓释 

分 类 号：TQ658.2[化学工程—精细化工] O657.33[理学—分析化学]