甲磺酸培氟沙星与氯冉酸的荷移反应  

Charge Transfer Reaction of Pefloxacin Mesylate with Chloranilic Acid

作　　者：庞秋霞[1] 孙雪花[2] 柴红梅[2] 高楼军[2] 刘芳玲[2] 

机构地区：[1]延安大学医学院 [2]延安大学化学与化工学院

出　　处：《光谱实验室》2013年第4期1968-1971,共4页Chinese Journal of Spectroscopy Laboratory

基　　金：陕西省重点实验室项目(12JS119);延安大学大学生创新计划项目(YD2012-08)

摘　　要：利用甲磺酸培氟沙星与氯冉酸在甲醇介质发生荷移反应,建立了荷移分光光度法测定甲磺酸培氟沙星含量的方法。结果表明,荷移反应生成1∶1型配合物,最大吸收波长为530nm,甲磺酸培氟沙星线性范围为2.25×10-8—3.38×10-6mol/L浓度内,回收率为98.7%—101.4%。Base on the charge-transfer reaction between pefloxacin mesylate and chloranilic acid in methanol solution,a spectrophotometric method was established for the determination of pefloxacin mesylate in preparations.The experimental results show that the composition ratio of the complex is 1∶1,the linear range of the determination is 2.25×10-8—3.38×10-6mol/L,at maximum absorption wavelength 530nm,and the recovery is 98.7% to 101.3%.

关 键 词：分光光度法 荷移反应 甲磺酸培氟沙星 氯冉酸 

分 类 号：O657.32[理学—分析化学]