2型糖尿病患者血清踝肱指数、趾肱指数和肱踝脉搏波速度改变及其影响因素的观察  

Observation of changes in ABI,TBI,and baPWV and their influencing factors in T2DM patients

作　　者：董晓云[1] 张磊[2] 李娟娟[2] 钱薇薇[1] 姜国辉[3] 董砚虎[2] 

机构地区：[1]青岛市内分泌糖尿病医院特检科,266071 [2]青岛市内分泌糖尿病医院内科,266071 [3]潍坊医学院内科学教研室

出　　处：《中国糖尿病杂志》2013年第7期597-598,共2页Chinese Journal of Diabetes

摘　　要：目的探讨T2DM患者踝肱指数(ABI)、趾肱指数(TBI)和肱踝脉搏波速度(baPWV)改变及相关危险因素。方法测定ABI、TBI及baPWV、实验室及人体测量学指标,进行分析比较。结果与NC组相比,T2DM组baPWV升高、TBI降低(P<0.05)。年龄是ABI和TBI异常的相关危险因素,年龄、DBP、2hPG和HbA1c是baPWV异常的相关危险因素,HDL-C是TBI的保护因素。结论动脉硬化检测可评价T2DM患者动脉弹性,积极控制血压和血糖可延缓动脉硬化进程。Objective To investigate the changes in ankle-brachial index （ABI）, toe brachial index （TBI）, and brachial-ankle pulse wave velocity （baPWV） and their related factors in the T2DM patients. Methods The baPWV, ABI, TBI, laboratory and anthropometric indicators of the subjects were measured and analyzed. Results Compared with the control group, baPWV significantly increased, and TBI significantly decreased in the diabetic group （all P〈0. 05）. Age was the risk factor for ABI and TBI abnormalities. Age, DBP, 2 hPG, and HbA1 c were the risk factors for baPWV abnormality. And HDL-C was a protective factor for TBI （P〈0. 05）. Conclusion Arteriosclerosis detecting indexes can be used to evaluate arterial elasticity in diabetic patients. Active control of blood pressure and blood glucose can slow down the atherosclerosis process.

关 键 词：糖尿病 2型 踝肱指数 肱踝脉搏波传导速度 趾肱指数 

分 类 号：R587.1[医药卫生—内分泌]