eds1、atr/nrc1、ahl19三个抗病相关的防卫基因的研究进展  

Progress on Three Defence Genes eds1,atr/nrc1 and ahl19

作　　者：齐希梁[1] 程红梅[1] 

机构地区：[1]中国农业科学院生物技术研究所,北京100081

出　　处：《生物技术进展》2013年第4期238-242,共5页Current Biotechnology

基　　金：国家转基因生物新品种培育重大专项(2011ZX08005-004-003)资助

摘　　要：防卫基因在植物抗病分子生物学的的研究中起到重要的作用。本文综述了抗病相关基因eds1、atr/nrc1、ahl19在防卫病原微生物入侵时的机理及在信号通路中的作用。EDS1是依赖水杨酸的抗性途径TIR-NB-LRR类R蛋白防御中的一个必需的基本元件;AHL19是防卫病原菌入侵时是一个关键的调控元件,防卫病原菌入侵的信号通路还有待探索;NRC1是HR关联的细胞程序性死亡的抗性蛋白Cf-9、Pto和Rx途径中的必需因子。这些基因的研究有助于植物抗病分子育种研究,尤其是针对缺少抗原的重大病害(如棉花黄萎病)提供了获得转基因新品种的可能性。Defence genes play an important role in plant resistant to disease. In this paper we introduce three defence genes＇ （edsl ,atr/nrcl and ah119） function in defenses to pathogens and the role in their signal pathway. EDS1 encodes an essential component of disease resistant R genes in salicylic acid dependent resistance pathway TIR-NB-LRR class. AHL19 acts as a positive regulator of plant defense. NRC1 is also required for the HR pathway induced by the R proteins Cf-9, Pto and Rx. It provides theoretical basis to explore the mechanism of plant resistance to disease, especially to the plants which lack the antigen to the disease such as cotton Verticillium Wilt. It is possible to breed new varieties with high resistance to Verticillium Wilt of cotton by using those defence genes.

关 键 词：eds1基因 atr/nrc1基因 ahl19基因 抗病 信号通路 防卫基因 

分 类 号：S432.2[农业科学—植物病理学]