正骨水中徐长卿的提取工艺优化  

Optimization of Extraction Technology for Cynanchum paniculatum in Zhenggu Mixtures

作　　者：覃葆[1] 李琴 邓欢[1] 蒋文佳[1] 韦东晓[1] 仝丹丹[1] 贺勤[1] 

机构地区：[1]广西中医药大学,南宁530001 [2]广西玉林制药集团有限责任公司,广西玉林537001

出　　处：《中国实验方剂学杂志》2013年第14期47-49,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家科技特派员项目(2009GJE10028)

摘　　要：目的:优选正骨水中徐长卿的提取工艺。方法:以丹皮酚提取量为指标,采用正交试验考察粉碎度、乙醇体积分数及提取时间对提取工艺的影响,通过HPLC测定丹皮酚含量。结果:最佳提取工艺为粉碎度20目,加70%乙醇浸提60 h,丹皮酚提取量5.34 mg.g-1。结论:该工艺稳定可行,为正骨水的工业生产提供参考。Objective： To optimize extraction technology of Cynanchum paniculatum in Zhenggu mixtures.Method： With the content of paeonol as index,which was determined by HPLC,effect of grinding degree,ethanol concentration and extraction time on extraction technology was investigated by orthogonal test.Result： Optimum extraction technology conditions were as follows： grinding degree of raw material 20 mesh,maceration extracted 60 h with 70% ethanol,yield of paeonol 5.34 mg.g-1.Conclusion： Optimized technology was stable and feasible,this study could provide a reference for industrial production of Zhenggu mixtures.

关 键 词：正骨水 徐长卿 丹皮酚 

分 类 号：R283.6[医药卫生—中药学]