Kováts保留指数在中药挥发油成分定性中的作用—青皮  

Study on the Role of Kováts Retention Index for the Identification of Components in Essential Oil from Chinese Materia Medica as Citri Reticulatae Pericarpium Viride

作　　者：王坚[1,2] 陈鸿平[1] 刘友平[1] 刘荣[1] 樊丹青[1] 

机构地区：[1]成都中医药大学药学院,中药资源系统研究与开发利用省部共建国家重点实验室培育基地,成都611137 [2]重庆医科大学中医药学院,重庆400016

出　　处：《中国实验方剂学杂志》2013年第14期92-96,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金项目(81072991);四川省教育厅自然科学重点项目(09ZA033)

摘　　要：目的:以青皮为例,研究在质谱定性的基础上,保留指数在中药挥发油成分鉴定中的作用。方法:GC-MS测定青皮挥发油及参比物(系列正构烷烃)的总离子流谱图。根据相关公式计算各待鉴定化合物的保留指数。应用MS与保留指数结合的方式对化合物定性。结果:一些化合物具有几乎相同的质谱,通过保留指数的差异却可以区分它们。结论:保留指数在中药挥发油成分定性中发挥着重要作用。Objective： To study the function of retention index（RI） on the qualitative results based on the MS qualitative outcome of volatile oil from Chinese material medica（CMM） as Citri Reticulatae Pericarpium Viride（CRPV）.Method： The total ion chromatograms from essential oil of CRPV and referred materials as series n-alkanes were gotten by the GC-MS.The RIs of constituents in volatile oil were calculated by a related formula.The components were recognized by MS and RIs.Result： Some compounds have essentially identical mass spectra,while they can be discriminated by RIs.Conclusion： RI plays an important role in the identification of constituents in essential oil from CMM.

关 键 词：保留指数 青皮 挥发油 定性 气相色谱质谱联用仪 

分 类 号：R284.1[医药卫生—中药学]