口服补液盐治疗儿童直立性低血压的疗效评价  

Effect assessment of oral rehydration salts treating orthostatic hypotension in children

作　　者：袁鹤立[1] 李芳[1] 王成[1] 林萍[1] 康美华[1] 祝立平[1] 吴礼嘉[1] 许毅[1] 

机构地区：[1]中南大学湘雅二医院儿童医学中心儿童心血管专科,中南大学儿科学研究所,长沙410011

出　　处：《中华实用儿科临床杂志》2013年第13期977-979,共3页Chinese Journal of Applied Clinical Pediatrics

基　　金：“十二五”国家科技支撑计划（2012BA103803）;湖南省自然科学基金项目（13JJ5014）

摘　　要：目的 探讨口服补液盐（ORS）治疗儿童直立性低血压（OH）的疗效。方法 选取2009年10月至2012年1月在中南大学湘雅二医院儿童晕厥专科门诊就诊或住院的不明原因晕厥或先兆晕厥且行直立倾斜试验（HUTT）诊断为OH 的患儿12例。男5例，女7例；年龄6～14岁［（10.25 ±2.86）岁］。予 ORS治疗 14～493 d［（74.50±134.43）d］后随诊复查HUTT。采用SPSS16.0软件进行统计学分析。结果 1.血流动力学变化：HUTT开始前平卧位时心率（HR0）、HUTT开始后3 min时心率（HR3）、HUTT开始前平卧位时收缩压（SBP0）、HUTT开始后3 min时收缩压（SBP3）、HUTT开始前平卧位时舒张压（DBP0）治疗前后比较差异均无统计学意义（P均 〉0.05），HUTT开始后 3 min舒张压（DBP3）治疗后较治疗前明显升高［（68.42 ±7.01） mm Hg（1 mm Hg=0.133 kPa）比（57.83±13.98）mm Hg，t= -2.344，P 〈0.05］。复查 HUTT时 OH 儿童晕厥、先兆晕厥等症状减轻5例，消失7例。2.血流动力学变化的性别比较：治疗前及治疗后HR0、HR3、SBP0、 SBP3、DBP0、DBP3男女比较差异均无统计学意义（P均 〉0.05）。结论 ORS能明显提高 OH 患儿舒张压，改善直立不耐受症状。Objective To explore the curative effect of oral rehydration salts（ORS） treating orthostatic hypo-tension （OH） in children. Methods Twelve OH children [ 5 male, 7 female, 6 - 14 years old, mean （ 10.25 ± 2.86 ） years old] ,who came from children syncope out-patient department or in-patient department of the Second Xiangya Hospital of Central South University from Oct. 2009 to Jan. 2012, complaining of syncope or pre-syncope symptoms and turned out to be HUTT positive were enrolled in this study. ORS was given（ 14-493 ） days, mean（ 74.50 ±134.43 ） days after the follow-up review the HUTT. The SPSS 16.0 software was used for statistical analysis. Results 1. Hemo-dynamic changes ： there was no statistical difference in heart rate of HUTY starting before （HRO） and heart rate of HUTT starting after 3 min（ HR3 ） and systolic blood pressure of HUTY starting before（SBPO） and systolic blood pressure of HUTT starting after 3 min （SBP3） and diastolic blood pressure of HUTT starting before （DBP0） between male and fe- male OH childern （ all P 〉 0.05 ）. Diastolic blood pressure of HUTT starting after 3 rain （ DBP3 ） in after treatment was significantly higher than that in before treatment [ （68.42 ± 7.01 ） mm Hg vs （57.83 ± 13.98 ） mm Hg, t = - 2. 344, P 〈0.05]. When the HUTT reexamine OH children symptoms of syncope and pre-syncope were fade（n =5） or disap-pear（ n = 7 ）. 2. Gender compare of hemodynamic changes before and after treatment ： there was no statistical difference in HRO and HR3 and SBP0 and SBP3 and DBPO and DBP3 between male and female OH childern （ all P 〉 0. 05 ）. Conclusions ORS can obviously increase diastolic blood pressure and improve the upright intolerance symptoms in OH children.

关 键 词：口服补液盐 直立性低血压 治疗 儿童 

分 类 号：R725.4[医药卫生—儿科]