糖苷合成研究(XV) 2-苯硫基-5-氟-3H-4-嘧啶酮糖苷的合成和表征  

STUDIES ON THE SYNTHESIS OF GLYCOSIDES(XV) —— THE SYNTHESIS AND CHARACTERIZATION OF GLYCOSIDES OF 2-PHENYLTHIO-5-FLUORO-3H -4-PYRIMIDINONE

作　　者：孙昌俊[1] 戚聿新[1] 李爱霞 李洪祥[1] 张华坤[2] 

机构地区：[1]山东大学化学学院,山东济南250100 [2]山东大学生命科学院,山东济南250100

出　　处：《山东大学学报（自然科学版）》2000年第3期305-309,共5页Journal of Shandong University(Natural Science Edition)

摘　　要：采用相转移催化法和Koenigs Knoor反应 ,使乙酰基 α D 溴代糖 1与 2 苯硫基 5 氟 3H 4 嘧啶酮 2 (或其银盐 4 )反应 ,合成了 5个相应的糖苷类化合物 ,其结构经IR、1HNMR和元素分析所证实 .Two N glycosides 3(A B) of 2 Phenylthio 5 fluoro 3H 4 pyimidinone 2 were synthesized by the reaction of 2 with α bromoacetylglycose 1(A B) under phase trasfer catalysis, and three O glycosides 5(A C) of 2 were prepared by the Koenigs Knoor reaction of 1(A C)with the silver salt 4 of 2.Their structure were confirmed by IR. 1HNMR and elementary analysis.

关 键 词：糖苷 合成 表征 2-苯硫基-5-氟-3H-4-嘧啶酮糖苷 

分 类 号：O629.13[理学—有机化学] R979.1[理学—化学]