西酞普兰对产后抑郁的早期干预影响  

Early Intervention to Post-natal Depression by Using Citalopram.

作　　者：孙佳文[1] 甄庆伟 

机构地区：[1]河北省唐山市截瘫疗养院,063000

出　　处：《中国健康心理学杂志》2013年第7期968-969,共2页China Journal of Health Psychology

摘　　要：目的观察西酞普兰对产后抑郁早期干预疗效。方法筛查产后抑郁患者110例,随机分为研究组和对照组各55例,对照组给予一般性对症处理,研究组在此基础上使用西酞普兰进行抗抑郁治疗,疗程12周,于入组、治疗第2、4、6、8、12周进行HAMD评定。结果对照组各周抑郁值一直维持在较高水平,研究组自第2周开始持续改善至治疗结束(t=7.28,17.18,21.57,33.14,36.12;P<0.01);两组于治疗各周HAMD比较有明显差异(t=6.38,25.41,40.09,85.94,72.79;P<0.01)。结论使用西酞普兰对筛查出的产后抑郁患者早期干预能显著改善症状,促进患者全面康复。Objective To observe curative effect of early intervention on patients by with post-natal depression using citalopram.Methods A total of 100 cases who were selected by using EPDS were divided into study group and control group.General treatment was used in control group and citalopram in study group for 12 weeks.To test at the time of 0,2,4,6,8,12 weeks by HAMD.Results Scores of HAMD maintained high level each week in control group and began to improved since 2 weeks to end in study group（t=7.28,17.18,21.57,33.14,36.12;P0.01）;There were significant differences between two groups each week（t=6.38,25.41,40.09,85.94,72.79;P0.01）.Conclusion Citalopram can improve the symptom of patients with post-natal depression,and improve the rehabilitation.

关 键 词：产后抑郁 西酞普兰 早期干预 汉密尔顿抑郁量表 

分 类 号：R714.46[医药卫生—妇产科学]