胎盘异常血池与妊娠结局的相关性研究  

Correlation between abnormal placental blood pool and pregnancy outcomes

作　　者：罗斐[1] 谢红宁[1] 李丽娟[1] 杨建波[2] 李岚[1] 朱云晓[1] 

机构地区：[1]中山大学附属第一医院妇产超声科,广州510080 [2]中山大学附属第一医院产科,广州510080

出　　处：《中华生物医学工程杂志》2013年第2期123-127,共5页Chinese Journal of Biomedical Engineering

基　　金：国家自然科学基金（81071166）

摘　　要：目的探讨胎盘内异常血池超声声像特征与胎儿及围生儿结局的相关性。方法本院2011年10月至2012年8月产前超声检查发现胎盘内异常血池声像的妊娠病例55例（胎盘血池组），另完全随机选择同期妊娠无胎盘内异常血池30例为对照组。采用前瞻性队列研究比较两组胎儿及同生儿结局，优势比（oR）分析胎盘内异常血池与胎儿及围生儿结局的关联程度。结果胎盘血池组中剖宫产率、胎儿宫内生长受限、早产儿、低出生体质量儿、低Apgar评分及转新生儿重症监护室（NICU）发生率均高于对照组（P〈0．05），但两组问胎儿窘迫及高危儿的发生率差异无统计学意义（16．4％比6．7％，27．1％比10．0％，P〉0．05）。胎盘血池组中胎儿生长受限、低出生体质量儿、新生儿转NICU等发生风险均高于对照组（OR〉1）。结论胎盘内异常血池声像与胎儿及围生儿不良预后显著相关，可作为预测胎儿不良结局的风险指标。Objective To investigate the correlation between the uhrasonographic imaging characteristics of abnormal placental blood pool and the outcomes in fetal and perinatal infants. Methods A total of 55 pregnant women who underwent ultrasonography for prenatal investigations showing abnormal placental blood pool （abnormal placental blood pool group ） and 30 random consecutive pregnant women without evidence of abnormal placental blood pool （ control group） in The First Affiliated Hospital of Sun Yat-sen University between October 2011 and August 2012 were enrolled in the study. Prospective cohort study design was applied to compare fetal and perinatal infant outcomes, and the odds ratio（OR） was employed to analyze the correlation between abnormal placental blood pool and outcomes in fetal and perinatal infants. Results Compared with control group, a higher incidence of cesarean section, fetal growth restriction （FGR）, preterm infant, low birth weight infant and newborn referral to NICU and lower Apgar score was noted in placental blood pool group （P〈0.05）. However, the difference of incidence in intrauterine fetal distress and high-risk infant was unremarkable（ 16.4% vs 6.7%, 27.1% vs 10.0%, both P〉0.05 ）. The placental blood pool group had increased risks of FGR, low birth weight infant and newborn referral to NICU than control group （OR〉I）. Conclusion The abnormal placental blood pool correlates significantly with the adverse prognosis of fetal and perinatal infants and may be an effective indicator of adverse pregnancy outcomes.

关 键 词：胎盘血液循环 超声检查 妊娠结局 围生儿 

分 类 号：R44[医药卫生—诊断学] R714[医药卫生—临床医学]