深圳地区2011～2012年急性上呼吸道感染鼻病毒检测分析  

Detection and analysis of rhinovirus in acute upper respiratory tract infections in Shenzhen area from 2011 to 2012

作　　者：余光清[1] 黄运美[1] 茌静[1] 雷蕾[1] 张震文[1] 

机构地区：[1]深圳市宝安区疾病预防控制中心,广东深圳518101

出　　处：《中国热带医学》2013年第5期575-577,共3页China Tropical Medicine

基　　金：深圳市宝安区科技计划项目(No.2010642)

摘　　要：目的了解深圳地区急性上呼吸道感染患者中的鼻病毒感染状况及流行特征。方法采用实时荧光定量PCR法,对采集深圳市宝安区人民医院635份咽拭子样本进行鼻病毒检测。结果 2011～2012年急性上呼吸道感染患者鼻病毒的阳性率为18.27%(116/635),HRV感染主要集中在7岁以下儿童,占64.66%(75/116),其中幼儿检出率最高,其次婴儿和学龄前儿童。HRV主要在春、夏、秋季检出,冬季检出较少。结论鼻病毒是深圳地区急性上呼吸道感染患者的主要病原体,随着季节和年龄的不同而具有一定的流行规律。Objective To investigate the epidemiological features of the human rhinovirus（HRV）in acute upper respiratory tract infections in Shenzhen.Methods Rhinovirus was detected in 635 clinical swabs by real-time fluorescent quantitative PCR.Results The positie rate of HRV was 18.27%（116/635）,most cases（64.66%）were under 7 years old,the detection rate of human rhinovirus in young child was higher,followed by infants and preschool child.The infection rate of human rhinovirus in Spring,Summer and Autumn was significantly higher than that in Winter.Conclusions Human rhinovirus is one of the most important pathogens for acute upper respiratory tract infection in Shenzhen area,showing seasonal feature3s and mainly infect children under 7 years old.

关 键 词：急性上呼吸道感染 鼻病毒 荧光定量PCR 

分 类 号：R373.1[医药卫生—病原生物学]