玉丹荣心丸治疗手足口病并心肌损害患儿的疗效分析  

Effects of the treatment that given Yudanrongxin pills on hand-foot-mouth disease with cardiac damage

作　　者：袁丽君[1] 

机构地区：[1]河南省漯河市中心医院儿科,河南漯河462000

出　　处：《中国医药科学》2013年第13期73-74,共2页China Medicine And Pharmacy

摘　　要：目的观察玉丹荣心丸治疗手足口病并心肌损害患儿的疗效。方法选择80例手足口病合并心肌损害患儿,随机分为观察组和对照组,均根据指南常规治疗,观察组加用荣心丸治疗,对两组治疗前后心肌酶谱(CK,CK-MB,LDH,AST和HBDH)的检测结果进行对比。结果治疗后观察组CK、CK-MB和LDH分别是(163.17±48.94)U/L、(16.83±6.06)U/L和(217.67±53.48)U/L,低于对照组CK(222.75±80.96)U/L、CK-MB(21.92±5.30)U/L和LDH(269.50±59.23)U/L,差异有统计学意义(P<0.05)。两组均未发现明显的不良反应。结论在常规治疗基础上加用玉丹荣心丸治疗手足口病并发心肌损害,有助于缩短病程,提高临床疗效。Objective To study and analyze the effect of the treament that given Yudanrongxin pills on hand-foot- mouth disease with cardiac damage. Methods Eighty patients with hand-foot-mouth disease,which were complicated by cardiac damage, were divided into observation group and control group,with 40 patients in each group. All patients received conventional treatment. On the basis,the observation group was given Yudanrongxin pills. The treatment course was 7 days. The levels of creatine kinase（CK）,creatine kinase-MB（CK-MB）,aspartate aminotransferase（AST）,lactate dehydrogenase（LDH） and hydroxybutyrate dehydrogenase（HBDH） were compared between the two groups. Results After treatment, the levels of CK,CK-MB and LDH were significantly lower in observation group than that in control group [（163.17 ± 48.94）U/L vs.（222.75± 80.96）U/L,P 〈 0.05.（16.83 ± 6.06）U/L vs.（21.92± 5.30）U/L,P 〈 0.05. （217.67 ± 53.48）U/L vs. （269.50 ± 59.23）U/L,P 〈 0.05],respectively. No side effects were found in all patients. Conclusion The treatment that given Yudanrongxin pills on the conventional treatment is effective and safe for hand- foot-mouth disease with cardiac damage and is worthy of clinical application.

关 键 词：手足口病 心肌损害 玉丹荣心丸 

分 类 号：R725.1[医药卫生—儿科]