母体维生素D缺乏对妊娠及后代的影响  

Effects of maternal vitamin D deficiency on pregnancy and offspring

作　　者：刘睿[1] 苗巍[1] 关海霞[1] 

机构地区：[1]中国医科大学附属第一医院内分泌科,内分泌研究所,辽宁省重点实验室,沈阳110001

出　　处：《国际内分泌代谢杂志》2013年第4期276-278,286,共4页International Journal of Endocrinology and Metabolism

摘　　要：维生素D不仅与钙、磷代谢以及骨骼运动系统有关，还与免疫调节、细胞分化和凋亡以及神经系统发育有关。妊娠期母体的维生素D水平对孕妇及后代都有重要的影响。目前有研究表明：先兆子痫、妊娠期糖尿病、细菌性阴道炎和早产等与母体维生素D缺乏关系密切，后代的骨营养不良、呼吸道感染、哮喘和其他自身免疫疾病也与母体妊娠期维生素D缺乏相关。妊娠女性维生素D缺乏很常见，因而适当补充维生素D十分必要。Vitamin D is not only involved in its classic function in bone homeostasis, but also plays an important role in immunological regulation, cell differentiation and apoptosis, and nerve system develop-ment. The level of maternal vitamin D has a great effect on pregnant women and their offsprings. Recent re-searches have shown that preeclampsia, gestational diabetes, bacterial vaginosis and preterm delivery may be associated with vitamin D deficiency. Moreover, vitamin D deficiency during pregnancy could also lead to bone dysplasia, respiratory infections, asthma and some autoimmune diseases in the offsprings. Pregnant women take a higher risk of vitamin D deficiency, so it＇s necessary to supplement vitamin D properly.

关 键 词：维生素D 妊娠 后代 

分 类 号：R714.2[医药卫生—妇产科学]