876例晚期妊娠胎盘病理临床研究  

Clinical analysis of the placental pathology of 876 late pregnancy cases

作　　者：范朝梅[1] 林锦芬[1] 吴长春[2] 

机构地区：[1]福建中医药大学附属厦门市中医院产科,福建厦门361009 [2]福建省厦门市疾病预防控制中心,361021

出　　处：《中国妇幼卫生杂志》2013年第3期9-10,共2页Chinese Journal of Women and Children Health

摘　　要：目的研究晚期妊娠胎盘病理变化与妊娠并发症及围产儿结局的关系。方法选择2010年6月-2012年12月在厦门市中医院876例晚期高危妊娠分娩后胎盘均送病理检查的临床资料,分析胎盘病理变化与妊娠并发症的关系;特别分析其中最常见的两类胎盘病理变化:炎症性变化、绒毛缺血缺氧病变对围产儿结局的影响,取炎症性病变组359例,绒毛缺血缺氧病变组387例,分别与正常胎盘组(送检无病理改变)89例作对照。结果送检胎盘876例,正常胎盘89例,占15.16%;有病理改变787例,占89.84%,其中胎盘形状及发育异常18.15%,炎症病变40.99%,绒毛缺血缺氧病变44.18%,肿瘤性病变1.37%。常见的炎症性病变组、绒毛缺血缺氧病变组中不良围产儿结局:如新生儿窒息、死胎的发生率与正常胎盘组比较,差异均有统计学意义(P<0.05)。结论胎盘的病理变化与妊娠并发症密切相关,尤其胎盘炎症性病变与胎盘绒毛缺血缺氧性病变可直接影响围产儿结局,必须重视胎盘的病理检查。[ Objective ] To investigate the relationship between the pathological changes of placenta in late pregnancy and complications and perinatal outcome. [ Methods ] A retrospective study design was used with 876 cases of high risk pregnant women whose placenta were sent for pathological examination, and then analyze the clinical data for studying the relationship between the pathological changes of placenta in late pregnancy and complications and perinatal outcome from June 2010 to December 2012 influence of inflammatory changes ~ Especially analyses the two most common types of pathological changes and villi hypoxicischemic lesion on perinatal ououtcome. We analyze the of placenta： 359 cases of inflammatory lesion group and 387 cases of villi hypoxicischemic lesion group, match with 89 cases of normal group （without pathological changes of placenta）. [ Resluts ] In all of the 876 cases of placenta samples, 89 cases were normal placenta, the rate of normal placenta is 15.16%. 787 cases have pathological changes, and the rate of placenta pathological changes is 89.84%. The pathological changes include the shape dysplasia （18.15%）, inflammation （40.99%）, villous hypoxia ischemia lesion （44.18%） and tumor （1.37%）. Adverse perinatal outcomes： such as infant asphyxia, incidence of stillbirth happened more in the common inflammatory lesions and villous hypoxia ischemia lesion group. The differences were significant differences in statistically~ （P 〈 0.05）0 [ Conclusions ] The pathological changes of placenta have close relationship to pregnancy complications and perinatal outcome, and placental inflammatory lesions and placenta ischemic lesion have a direct impact on perinatal outcome. So we should pay attention to pathological examination of the placenta.

关 键 词：胎盘病理 妊娠并发症 围产儿结局 

分 类 号：R714.2[医药卫生—妇产科学]