金泽冠心软胶囊制剂工艺研究  

Preparation Technology Reaserch of Jinze Guanxin Soft Capsule

作　　者：王贤英[1] 谢香菊[1] 李胜容[1] 

机构地区：[1]重庆市中药研究院,重庆400065

出　　处：《中国药业》2013年第15期59-61,共3页China Pharmaceuticals

基　　金：重庆市科技攻关项目(CSTC);项目编号:2009AB5177

摘　　要：目的研究金泽冠心软胶囊的最佳成型工艺。方法通过对软胶囊内容物和囊壳处方、软胶囊压制和干燥的关键生产工艺的优化研究,确定金泽冠心软胶囊的最佳成型工艺。结果最佳工艺为,胶囊壳处方明胶-甘油-水(10∶4∶10);内容物处方,金泽提取物为53%,大豆油为44%,蜂蜡为3%;干燥工艺,温度为25℃,相对湿度为25%～30%,干燥16 h。结论该处方工艺稳定、可靠,适用于金泽冠心软胶囊的工业化生产。Objective To reaserch the best forming technology of Jinze Guanxin Soft Capsule. Methods By optimizing the key produc- tion technology of the contents, capsule shell prescription, suppression and drying of soft capsule, the optimal forming technology of Jinze Guanxin Soft Capsule was determined. Results The best technology was obtained. The capsule shell prescription was gelatin-glycer-ine-water（10：4 ： 10）; the contents prescription was Jinze extract of 53%, soybean oil of 44% and beeswax of 3%;the drying process adopted the temperature of 25 ℃ with the relative humidity of 25% - 30%, and drying for 16 h. Conclusion This prescription technol-ogy is stable, reliable and suitable for the industrialization production of Jinze Guanxin Soft Capsule.

关 键 词：金泽冠心软胶囊 工艺 处方 

分 类 号：TQ461[化学工程—制药化工] R286[医药卫生—中药学]