脐血检测在早期新生儿感染诊断中的应用  

The application of umbilical blood detection to the diagnosis of inflammation in neonates

作　　者：李月(综述)[1] 王晓明(审校)[1] 

机构地区：[1]复旦大学附属上海市第五人民医院儿科,上海200240

出　　处：《国际儿科学杂志》2013年第4期375-378,共4页International Journal of Pediatrics

摘　　要：由于新生儿免疫功能尚不成熟，尤其是早产儿及低出生体重儿，易发生各种感染性疾病。新生儿败血症早期往往表现轻微，临床症状多不典型，因此寻找早期、有效的感染检测指标一直是研究的热点。随着检测技术的发展，目前国内外在外周血感染指标检测方面已取得显著进展，但有关脐血检测方面的研究尚处于起步阶段。与传统外周血检测相比，脐血检测具有早期、无创伤、安全、方便的优点。该文主要探讨脐血检测指标在早发型新生儿败血症诊断中的应用。Because of the neonatal immune system is immature,particularly in preterm and low birth weight infants, the neonate is prone to some infections. Neonatal sepsis usually has the slight performance and a- typical clinical symptoms, which raise the great interest of searching for some better biomarkers. With the devel- opment of testing technology, the research of serum inflammation marker has made remarkable progress at home and abroad in recent years, however, the research of umbilical blood inflammation marker is still in the early stage of exploration. Umbilical blood detection have the advantages of early, noninvasive, safe and convenient compare to the traditional serum detection. This paper mainly discusses the application of umbilical blood detec- tion to early onset neonatal sepsis.

关 键 词：新生儿 脓毒血症 降钙素原 C-反应蛋白 细胞因子 

分 类 号：R135.1[医药卫生—劳动卫生]