重症多形红斑型药疹23例回顾性分析  

A Retrospective Analysis of 23 Cases of Stevens-Johnson Syndrome

作　　者：周晴[1,2] 邵敏华[1] 施和建[1] 张国龙[1] 顾永[1] 杨挺[1] 浦洁[1] 

机构地区：[1]南京医科大学附属无锡市人民医院皮肤科,江苏无锡214023 [2]南京中医药大学附属无锡市中医医院皮肤科,江苏无锡214033

出　　处：《中国皮肤性病学杂志》2013年第8期801-802,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨重症多形红斑型药疹的诊治规律。方法回顾性分析本科2008年1月-2011年12月收治的23例重症多形红斑型药疹的临床资料。结果治愈21例,死亡2例。抗癫痫药、解热镇痛药及各种抗生素是主要致敏药物。该病极易并发肝、肾功能损害、低蛋白血症及各种感染。结论重症多形红斑型药疹是皮肤科的危重病症之一,有一定死亡率。及早并足量使用糖皮质激素、支持治疗和积极防治多种并发症是成功救治的关键。Objective To analyze the characteristic of the Stevens-Johnson syndrome and discuss it＇s diagnosis and treatment. Method A retrospective analysis on the clinical data of 23 patients who were admitted into our department from January 2008 to December 2011 were carried out. Results There were 21 cases were cured and 2 cases died in all 23 cases. Antiepileptic drugs, antipyretic analgesics and antibiotics were the main allergenic drugs. Liver and kidney damage, hypoproteinemia, and various infections were common complications. Conclusions Stevens-Johnson syndrome is one of the critical illness of Dermatology. Early and adequate use of glucocorticoids, supportive treatment and active prevention and treatment of complica- tions is the key of a successful treatment.

关 键 词：重症多形红斑型药疹 回顾性分析 

分 类 号：R758.25[医药卫生—皮肤病学与性病学]