三七止血片中三七含量测定  

Determination of Contents of Ginsenoside Rg_1 ,Ginsenoside Rb_1 and Notoginsenoside R_1 in Notoginseng Hemostasis Tablet

作　　者：沙延淳[1] 叶小辉[1] 杨祝仁[1] 姚建华[2] 

机构地区：[1]辽宁省药物研究院,辽宁沈阳110015 [2]辽宁中医药大学,辽宁大连116600

出　　处：《辽宁中医药大学学报》2013年第8期48-49,共2页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:对三七止血片中三七的主要成分进行测定,提高质控标准。方法:采用液相梯度法以人参皂苷Rg1、人参皂苷Rb1和三七皂苷R1的含量为指标。结果:测定三七止血片中人参皂苷Rg12.42 mg/片,人参皂苷Rb11.37 mg/片,三七皂苷R10.15 mg/片,含皂苷总量为3.94 mg/片。结论:液相梯度法方法可控,可以达到提高药品质量控制的目的。Objective： Determination of the contents of main components in notoginseng hemostasis tablet was made to improve the standard of quality. Methods ： The contents of ginsenoside Rgl, ginsenoside Rbl and the notoginsenoside R1 were set up as the indexes by HPLC gradient profile. Results ： The contents of ginsenoside Rgl, ginsenoside Rbland the notoginsenoside R1 were 2.42 mg per tablet, 1.37 mg per tablet and 0.15 mgper tablet respectively. 3.94 mg per tablet was the total saponin content. Conclusion：The exneriment of HPLC zradient orofile could reach the ~oal by improving quality control of the drug.

关 键 词：三七止血片 三七 含量 

分 类 号：R284.2[医药卫生—中药学]