雷公藤的毒性考证与预防分析研究  

Analysis on Study of Toxicity and Poisoning Prevention of Leigongteng

作　　者：李进[1] 王均宁[1] 张成博[1] 

机构地区：[1]山东中医药大学,山东济南250355

出　　处：《辽宁中医药大学学报》2013年第8期74-76,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)专项资助项目(2009CB522802)

摘　　要：该文从中毒机理与临床表现、中毒原因及中毒预防三个方面,总结分析了雷公藤中毒的相关研究。提出雷公藤中毒的原因主要与过量使用、用药部位差异、煎服方法不妥、炮制不当有关。其毒性主要表现在循环系统、免疫系统、消化系统、神经系统与生殖系统等方面的损害,急性肾衰竭、急性肝坏死、骨髓损伤与心肌损害是其主要致死原因。中毒预防应从剂量、用法、炮制及个体差异方面予以重视。This paper summarizes the toxicity of Leigongteng from toxin, clinical manifestation, poisoning reason and poisoning prevention. We draw the conclusion that the poisoning reason is relating to overuse, different pall of drugs, inappropriate methods of decoction and taking medicine, and improper way of refining Leigognteng. The effect of toxicity mainly damages circulatory system, immune system, digestive system, nervous system and urogenital system. The urgent renal failure, the urgent hepatic necrosis, the inju13, of bone marrow and the cardiac muscle damage are the cause of death. We should pay many attentions to the poisoning prevention on dosage, administration, refining herbs and individual diversity.

关 键 词：雷公藤 中毒反应 中毒原因 中毒预防 

分 类 号：R282.71[医药卫生—中药学]