苏黄止咳胶囊治疗咳嗽变异性哮喘的有效性研究  

Efficacy of Suhuang zhike capsule in patients with cough variant asthma

作　　者：熊宁[1] 彭志群[1] 吴金飞[1] 王强[1] 陈传琳 吴珊燕[1] 

机构地区：[1]解放军第一八四医院呼吸内科,江西省鹰潭市335000

出　　处：《中国医药》2013年第8期1071-1072,共2页China Medicine

摘　　要：目的 观察苏黄止咳胶囊治疗咳嗽变异性哮喘的临床疗效.方法 将80例咳嗽变异性哮喘患者完全随机分为2组,各40例.苏黄止咳胶囊组予以苏黄止咳胶囊,每次3粒,每日3次,温开水送服；博利康尼组予以博利康尼2.5 mg,每日3次.疗程均为4周.比较2组患者疗效和治疗前后IgG水平及气道阻力后.结果 苏黄止咳胶囊组治愈37例,好转3例,治愈率为92.5％；博利康尼组治愈29例,好转11例,治愈率为72.5％；苏黄止咳胶囊组治愈率明显高于博利康尼组,差异有统计学意义（P＜0.05）.苏黄止咳胶囊组治疗前IgG水平为（6.4 ±3.2）g/L,治疗后为（8.8 ±4.7）g/L,治疗前后差异有统计学意义（P＜0.05）；博利康尼组治疗前IgG为（6.5±2.9）g/L,治疗后为（7.2±3.8） g/L,治疗前后差异无统计学意义（P＞0.05）；苏黄止咳胶囊组治疗后IgG水平明显高于博利康尼组治疗后（P＜0.05）.苏黄止咳胶囊组治疗后呼吸总阻抗、总气道阻力、中心气道阻力均明显低于博利康尼组治疗后[（122±36）cm H2O（1 cm H2O=0.098 kPa）比（144±41）cm H2O,（118±32）cm H2O比（142 ±35）cm H2O,（83±26）cm H2O比（100±24）cm H2O],差异均有统计学意义（均P＜0.01）.结论 苏黄止咳胶囊治疗咳嗽变异性哮喘有较好疗效.Objective To observe the clinical efficacy of Suhuang zhike capsule in treatment of cough variant asthma（CVA）.Methods The CVA patients were randomly divided into Suhuang zhike capsule group and bricanyl group（40 cases in each group）.Suhuang zhike capsule group were treated with Suhuang zhike capsule.Bricanyl group were treated with bricanyl.Two groups were treated for 4 weeks.Results The cure rate of Suhuang zhike capsule group and bricanyl group was 92.5% （37/40）,72.5% （29/40）,and there was a significant difference （P 〈 0.05）.The serum total IgG in Suhuang zhike capsule group after treatment was （8.8 ± 4.7）g/L,which was higher than that before treatment [（6.4 ± 3.2） g/L,P 〈 0.05].The serum total IgG in bricanyl group after treatment was （7.2 ± 3.8） g/L,which was higher than that before treatment [（6.5 ± 2.9） g/L,P 〈 0.05].The airway resistance in Suhuang zhike capsule group postoperation were lower than those in bricanyl group after treatment [（122 ±36）cm H2O （1 cm H2O =0.098 kPa） vs （144±41）cm H2O,（118 ±32）cm H2O vs（142 ±35）cm H2O,（83 ± 26）cm H2O vs （100 ± 24）cm H2O; all P 〈 0.01].Conclusion Suhuang zhike capsule has a good effect on patients with CVA.

关 键 词：苏黄止咳胶囊 咳嗽变异性哮喘 气道高反应性 

分 类 号：R562[医药卫生—呼吸系统]