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作 者:刘晓红[1] 吴玉芙[1] 臧婷臻[1] 王浩然[1]
机构地区:[1]北京老年医院神经内科,100095
出 处:《中国医药》2013年第8期1081-1082,共2页China Medicine
摘 要:目的 探讨老年脑梗死患者发病的相关危险因素.方法 回顾性分析2010年10月至2012年3月北京老年医院收治的230例老年脑梗死患者临床资料,另选择150例老年非脑梗死患者作为对照组,采用多元Logistic回归模型分析其病因及危险因素.结果 非梗死组患者中颈动脉粥样硬化、高血压、高同型半胱氨酸血症、脂代谢异常和心房颤动所占比例明显低于脑梗死组患者[53.3% (80/150)比92.2% (212/230),59.3% (89/150)比74.3% (171/230),16.7% (25/150)比28.3% (65/230),30.0% (45/150)比41.7%(96/230),39.3% (59/150)比52.2% (120/230)],差异均有统计学意义(均P<0.05).高血压病、心房颤动、颈动脉粥样硬化、糖尿病为老年脑梗死主要的危险因素(P <0.05或P<0.01).结论 高血压病、心房纤颤、颈动脉粥样硬化、糖尿病是引起老年脑梗死的危险因素.根据存在的危险因素制订防治方案可有效降低该病的发生.Objective To investigate the risk factors of elderly patients with cerebral infarction.Methods All 230 cases of elderly patients with cerebral infarction were analyzed from October 2010 to March 2012; and the causes and risk factors were analyzed using multiple Logistic regression model.Results The ratio of atherosclerosis,hypertension,high blood homocysteine,abnormal lipid metabolism and atrial fibrillation ratio in non-infarction group were lower than those in the cerebral infarction group [53.3 % (80/150) vs 92.2% (212/230),59.3 % (89/150) vs 74.3 % (171/230),16.7 % (25/150) vs 28.3 % (65/230),30.0% (45/150) vs 41.7 % (96/230),39.3 % (59/150) vs 52.2% (120/230)],the difference was statistically significant (P 〈 0.05).Hypertension,atrial fibrillation,carotid atherosclerosis and diabetes were major risk factors (P 〈 0.05) ; the differences of other factors were not statistically significant (P 〉 0.05).Conclusion Hypertension,atrial fibrillation,carotid atherosclerosis and diabetes are independent risk factors of cerebral infarction.
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