在抢救口服有机磷中毒治疗过程中值得注意的问题  

Experience in Rescuing Patients with Acute Organophosphorus Pesticide Poisoning

作　　者：蒋红[1] 

机构地区：[1]安徽省宿州市第一人民医院急诊科,234000

出　　处：《中华全科医学》2013年第10期1544-1545,共2页Chinese Journal of General Practice

摘　　要：目的解决在抢救急性口服有机磷农药中毒过程中所应该注意的问题，提高抢救成功率，降低病死率。方法78例急性口服有机磷农药中毒患者，分为A、B两组，A组42例一次性洗胃后留置胃管，每隔3～4h洗胃一次，反复洗胃，24h后拔管，阿托品化后开始应用长托宁，B组36例一次性洗胃，未留置胃管，阿托品长托宁同时应用。结果A组患者，中毒症状改善快，胆碱酯酶活力恢复快，无明显药物副作用，无1例死亡，抢救成功率高，B组中毒症状改善慢，胆碱酯酶活力恢复慢，药物副作用明显，死亡3例，抢救成功率低。结论药物的合理选择，联合使用是抢救成功的关键，但在抢救过程中，及时反复彻底有效的洗胃，也是抢救成功的必要条件。Objective To summarize the experience in rescuing patients with acute organophosphorus pesticide poisoning,improve the success rate of rescue and therefore reduce the death rate. Methods All 78 patients with acute organophosphorus pesticide poisoning were randomly divided into two groups. Group A （42 cases） underwent a disposable gastrolavage and detaining gastric tube, then gastrolavage was performed every 3 -4 hours until 24 hours. Penehyclidine was followed after preliminary atro- pinization. Group B （36 cases） underwent a disposable gastrolavage;Atropine and Penehyelidine were administrated together. Re- sets The poisoning symptoms were improved quickly, cholinesterase activity recovered quickly without obvious side effect, no death case,the success rate was high as compared to group B. 3 cases died in the group B. Conclusion The combination of reasonable drugs is the key to successful rescue, but in the process of rescue, the timely, effective and repeated gastric lavaging is al- so the necessary condition.

关 键 词：急性有机磷中毒 长托宁 洗胃 

分 类 号：R595.51[医药卫生—内科学] R971.91[医药卫生—临床医学]