中国充分补碘地区不同人群血清甲状腺球蛋白正常值范围的研究  

Study on normal ranges of thyroglobulin of total population in iodine-replete region of China

作　　者：韩云峰[1] 刘守军[1] 

机构地区：[1]齐齐哈尔医学院公共卫生学院流行病与卫生统计学教研室,齐齐哈尔161006

出　　处：《卫生研究》2013年第4期581-584,共4页Journal of Hygiene Research

基　　金："十一五"国家科技支撑计划项目(No.2006BAI06B05)

摘　　要：目的通过对中国部分充分补碘地区人群血清甲状腺球蛋白的测定,以确定充分补碘地区正常人群的甲状腺球蛋白正常值范围。方法采用典型调查方法,收集中国6个地区4类目标人群(8～10岁儿童、18～45岁成人、孕妇和哺乳妇女)的晨起空腹血样,测定甲状腺球蛋白及其他甲状腺功能数据,对甲状腺功能正常人群的甲状腺球蛋白测定值进行统计分析。结果 6个地区人群甲状腺球蛋白95%正常值范围分别为:①8～10岁儿童:男(1.40,10.18)μg/L,女(1.41,11.44)μg/L;②18～45岁成人:男(1.55,39.88)μg/L,女(1.44,23.22)μg/L;③孕妇:(0.94,11.91)μg/L;④哺乳妇女:(0.12,15.05)μg/L。结论本研究建立了碘摄入正常情况下不同人群血清Tg含量的正常参考值范围,并建议将Tg纳入碘缺乏病的监测指标。Objective To deduce normal ranges of thyroglobulin of total population in iodine-replete region by determining the human serum thyroglobulin in normal population of part full iodine region.Methods Typical survey was used in this present study.Children aged 8-10 years,adults aged 18-45 years,pregnant woman and lactating women were chosen as our subjects.Morning fasting blood samples of subjects were collected.Thyroglobulin and thyroid function were determined,and the measured value of those subjects with normal thyroid function was analyzed.Results The normal ranges of thyroglobulin of the subjects were as following： Children aged 8-10 years： male（1.40,10.18） μg/L,female（1.41,11.44） μg/L,adults aged 18-45 years： male（1.55,39.88） μg/L,female（1.44,23.22） μg/L,pregnant woman：（0.94,11.91） μg/L,lactating women：（0.12,15.05） μg/L.Conclusion The research confirmed the serum Tg normal reference of different populations under the adequate iodine level,regarding this,Tg was adviced to be involed in the IDD survey indicators.

关 键 词：甲状腺球蛋白 参考值范围 甲状腺功能 

分 类 号：R591.1[医药卫生—内科学] R181.34[医药卫生—临床医学]