冠心病血浆致动脉硬化指数的临床研究  

Clinical Significance of Atherogenic Index of Plasma in Coronary Heart Disease

作　　者：郑家胜[1] 俎德玲[1] 诸葛毅[2] 屠晓鸣[1] 金奇志[1] 程科云[1] 

机构地区：[1]浙江省衢州市人民医院心内科,324000 [2]衢州职业技术学院医学院

出　　处：《心电与循环》2013年第4期263-265,共3页Journal of Electrocardiology and Circulation

摘　　要：目的观察冠心病患者血浆致动脉硬化指数的临床意义。方法经冠状动脉造影确诊为冠心病的患者192例,根据Gensini积分对冠状动脉病变程度进行评分并分级,健康体检者181例为对照组,同时测定血脂各成分及计算血浆致动脉硬化指数(AIP),分析冠状动脉病变与AIP之间的关系。结果冠心病组与对照组的AIP分别为:0.35±0.15和-0.03±0.1 8,差异有显著统计学意义(p<0.01)。冠状动脉轻度病变组,中度病变组,重度病变组AIP分别为0.20±0.11、0.32±0.10和0.43±0.1 1,差异有显著统计学意义(P<0.01)。结论 AIP与冠状动脉病变的严重程度相关。通过对AIP的观察,有可能初步预测冠状动脉病变。Objective To evaluate clinical value of atherogenic index of plasma （ALP） in patients with coronary heart disease（CAD）. Methods 192 patients with CAD confirmed by coronary angiography were enrolled, Coronary artery le- sion severity was determined by Gensini scale. 181 cases of healthy people were included in control group. Blood lipid parameters were measured and AlP was calculated. Results AlP was significantly higher in CAD patients 0.35 ±0.15 than in control group -0.03 ±0.18（P〈0.01）, and increased significantly from patients with mild 0.20 ±0.11, moderate 0.32 ± 0.10 to high 0.43 ± 0.11 lesions（P〈0.01）. Conclusion AlP is correlated with the severity of coronary artery lesions and may roughly predict coronary lesions.

关 键 词：冠心病 血浆致动脉硬化指数 冠状血管造影术 

分 类 号：R541.4[医药卫生—心血管疾病]