BODE指数评价慢性阻塞性肺疾病患者戒烟效果的研究  

The Effects of Quiting Smoking in Patients with Chronic Obstructive Pulmonary Disease Evaluated by BODE Index

作　　者：王少飞[1] 张庆[1] 韩玉杰[1] 姜峰[1] 李金玲[1] 

机构地区：[1]承德医学院附属医院呼吸科,河北承德067000

出　　处：《医学与哲学（B）》2013年第7期38-40,共3页Medicine & Philosophy(B)

基　　金：中华医学会临床医学慢性呼吸道疾病科研专项资金;项目编号:01070260034

摘　　要：采用BODE评分系统评价慢性阻塞性肺疾病(COPD)患者的戒烟效果。248例吸烟的稳定期COPD患者进行随机分组,一组除常规治疗外给予戒烟干预(即戒烟组),一组给予常规治疗(即对照组)。所有患者在入组时和观察结束时均给予肺功能检测、六分钟步行试验(6MWT)、呼吸困难评分(mMRC)、测量身高和体重,观察各指标的变化情况。至1年观察结束时,戒烟组和对照组在BMI(26.70±3.74vs.25.17±3.63)、FEV1%pred(50.29±12.54vs.46.68±15.37)、mMRC(1.64±0.90vs.2.53±1.07)、6MWD(306.84±27.71vs.257.84±30.34)方面分别比较,差异均有统计学意义(P<0.05);戒烟组患者研究结束时除FEV1%pred之外,其余观察指标BMI(26.70±3.74vs.23.11±3.51)、mMRC(1.64±0.90vs.2.18±0.91)、6MWD(306.84±27.71vs.281.15±32.40)与基线值比较均有所改善(P<0.05);对照组患者研究结束时除BMI之外,其余观察指标FEV1%pred(46.68±15.37vs.51.91±17.22)、mMRC(2.53±1.07vs.2.01±0.97)、6MWD(257.84±309.34vs.285.14±30.98)与基线值相比均有所下降(P<0.05)。COPD患者戒烟后其BODE评分系统中包括体重指数、肺功能指标、呼吸困难程度和运动能力在内的各个因素均得到一定程度的改善,生活质量显著提高。To study the effects of quitting smoking in patients with chronic obstructive pulmonary disease evaluated by BODE index, a total of 248 current smokers with stable COPD were randomly designed into two groups. One group received smoking cessation intervention besides conventional treatment. The other group only received conventional thera- py. All patients were evaluated pulmonary function test, 6MWT, mMRC, measurements of height and weight when enrolled and after the observation. Then explored the differences. Compared with the initial tests, 1 year later the BMI （26.70±3.74 vs. 25. 17±3. 63）, FEVI% pred （50.29±12.54 vs. 46.68±15.37）, mMRC （1.64± 0. 90 vs. 2.53±1.07）, 6MWD （306.84±27.7t vs. 257.84±30.34） in both two groups were significant,P〈0.05.1 year later, except the FEV1%pred, the BMI（26. 70±3. 74 vs. 23.11±3.51）, mMRC（1. 64±0. 90 vs. 2.18±0.91）, 6MWD（306. 84±27. 71 vs. 281.15±32.40） in smoking cssation group were better than the initial, P〈0.05. In control group,except the BMI, the FEV1% pred （46.68±15.37 vs. 51.91±17.22）, mMRC （2.53 ±1.07 vs. 2.01±0.97）, 6MWD （257.84±309.34 vs. 285.14±30.98）were worse compared with the initial,P〈0.05. After COPD patients quiting smoking, the BODE assess-ing system including body mass index, airflow obstruction, dyspnea and exercise capacity were improved to some extent. The quality of life in COPD patients were significantly improved.

关 键 词：慢性阻塞性肺疾病 戒烟 BODE评分 

分 类 号：R563[医药卫生—呼吸系统]