远程无线自控鞘内镇痛系统在晚期癌痛患者的疗效观察  

Analgesic effect of wireless patient-controlled intrathecal analgesia syetem in patients with late cancer pain

作　　者：贾宏彬[1] 宗健[2] 孙含哲[3] 金毅[1] 刘红军[1] 李伟彦[1] 徐建国[1] 

机构地区：[1]南京军区南京总医院麻醉科疼痛医学中心,210002 [2]无锡市第四人民医院麻醉科 [3]无锡市人民医院麻醉科

出　　处：《临床麻醉学杂志》2013年第7期672-674,共3页Journal of Clinical Anesthesiology

摘　　要：目的观察远程无线自控鞘内镇痛系统对晚期癌痛患者的镇痛效果。方法 21例晚期癌痛患者,采用远程无线自控鞘内镇痛系统,将改良埋入式注射泵植入皮下疏松结缔组织连接大容量无线自控镇痛泵持续注药镇痛。药物配方:盐酸罗哌卡因或布比卡因+盐酸吗啡注射液。记录治疗前、治疗后1、7、15、30d的疼痛强度评分(NRS评分)和睡眠评分。观察低颅压头痛、恶心呕吐、尿潴留、下肢肌力减退、感染、皮肤瘙痒等不良反应。结果与治疗前比较,治疗后1、7、15、30d患者NRS评分明显降低,睡眠评分明显升高(P<0.01);治疗后7、15、30d低颅压头痛、恶心呕吐等不良反应发生率明显低于治疗后1d(P<0.05)。结论改良埋入式无线自控鞘内镇痛治疗于晚期癌痛安全有效。Objective To observe the analgesia effect of wireless patient-controlled intrathecal analgesia syetem （WPCIAS） in 21 patients with late cancer pain. Methods Modified embedded intrathecal injection pump, which was implanted under the skin loose connective tissue was connected with big capacity wireless patient-controlled analgesia pump to continuously inject drugs to reduce pain. Drug composition： ropivacaine,or bubicacine and morphine. The NRS scores and quality of sleep of patients were recored before treatment and at 1,7,15,30 d after treatment. Results Compared with before treatment the NRS scores were significantly decreased, the quality of sleep of patients was improved significantly at 1,7, 15,30 d after treatment. Candusion WPCIAS could provide a safe and effective method for late cancer pain treatment.

关 键 词：自控鞘内镇痛系统 顽固性疼痛 吗啡 

分 类 号：R614[医药卫生—麻醉学]