男男性行为人群队列失访情况及影响因素分析  

Loss to follow-up and associated factors in a cohort study among men who have sex with men

作　　者：周楚[1] 徐杰[1] 斗智[1] 米国栋 阮玉华[1] 申莉梅[3] 闵向东[4] 蓝光华[5] 李凡[6] 李恬 宁镇[8] 吴国辉[9] 吴尊友[1] 

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心,北京102206 [2]中美艾滋病防治合作项目办公室 [3]贵州省疾病预防控制中心 [4]云南省疾病预防控制中心 [5]广西壮族自治区疾病预防控制中心 [6]新疆维吾尔自治区疾病预防控制中心 [7]成都市疾病预防控制中心 [8]上海市疾病预防控制中心 [9]重庆市疾病预防控制中心

出　　处：《中华流行病学杂志》2013年第8期788-791,共4页Chinese Journal of Epidemiology

基　　金：“十一五”国家科技重大专项（2008ZX10001-016）;中国多学科艾滋病结核防治培训项目（5U2RTW006918）

摘　　要：目的了解男男性行为人群（MSM）队列研究中失访人群特征及失访率水平，分析造成失访可能的影响因素。方法于2009年6—10月在8个城市开展基线调查，收集人口学、性行为特征等信息，并进行HIV、单纯疱疹病毒和梅毒检测。在基线调查基础上建立MSM队列后的第6个月和第12个月对队列进行两次随访，记录所有队列成员的失访情况。通过单因素分析和二分类logistic回归分析，了解各因素对失访的影响。结果在基线调查基础上建立3196人的MSM研究队列。在1年随访期间内，共有894人（28．0％）失访，2302人（72．1％）至少参加一次随访。单因素和多因素分析结果显示，研究对象年龄、在本地居住时间≤1年、无业、最近1年未接受HIV检测、个人性取向为双性或异性恋、最近6个月发生异性性行为是队列失访的危险因素。结论年龄、在当地居住时间、性取向和HIV检测史等因素与MSM队列失访有关，故在开展MSM队列研究时，应考虑这此因素。Objective To explore the associated factors on loss to follow-up among men who have sex with men （MSM） in a prospective cohort study. Methods We recruited eligible HIV-negative MSM at baseline in eight cities from June to October 2009. Interviewer-administrated questionnaire and blood testings for HIV, syphilis and human simplex virus type 2, were accomplished upon enrollment, 6-month and 12-month follow-up visits in the program. Loss to follow-up was recorded at each visit in this cohort. Univariate and multivariate statistical analysis were conducted to examine the associated factors on loss to follow-up. Results A total of 3196 eligible MSM were enrolled at the baseline study. During one year of follow-up, 894 （28.0%） of them dropped out thoroughly while 2302 （72.1% ） showed up at least on one visit. Factors as MSM who were at age 25 or younger, resided locally less than 1 year, being unemployed, self-recognized as heterosexuality or bisexuality, never taking HIV testing in the past year, having had sex with women in the past 6 months etc., were more likely to withdraw from the follow-up visits. Conclusion Age, length of residency, sex orientation and history of HIV testing were associated with the loss of follow-up among MSM cohort in our study. These factors should be considered in this kind of study design in the future.

关 键 词：男男性行为人群 队列研究 失访 影响因素 

分 类 号：R195[医药卫生—卫生统计学]