男男性行为者梅毒合并HIV感染影响因素分析  

Factors associated with syphilis-HIV co-infection among men who have sex with men in Shenzhen city

作　　者：蔡于茂[1] 宋亚娟[1] 潘鹏[1] 洪福昌[1] 冯铁建[1] 

机构地区：[1]深圳市慢性病防治中心性病防治科,广东518020

出　　处：《中国公共卫生》2013年第8期1127-1130,共4页Chinese Journal of Public Health

摘　　要：目的了解深圳市男男性行为者(MSM)梅毒合并人类免疫缺陷病毒(HIV)感染分布特征及其影响因素。方法对2005—2011年广东省深圳市MSM梅毒/HIV监测资料进行Cochran-Armitage趋势检验和logistic回归分析。结果 5 232例接受自愿咨询检测MSM中梅毒感染率为20.97%,HIV感染率为6.46%,梅毒合并HIV感染率为3.56%;2005—2011年深圳市MSM人群梅毒合并HIV感染率呈上升趋势(Z=-3.735 9,P=0.000 2);多因素logistic回归分析结果显示,MSM年龄≥40岁者梅毒合并HIV感染的危险性是年龄<40岁者的2.165倍(OR=2.165),大专及以上文化程度者梅毒合并HIV感染的危险性是初中及以下者的0.522倍(OR=0.522),性角色以主动为主者和主、被动二者兼有者梅毒合并HIV感染的危险性分别是被动为主者的0.388倍(OR=0.388)和0.606倍(OR=0.606)。结论广东省深圳市MSM人群梅毒合并HIV感染率呈上升趋势,有针对性地开展梅毒/HIV预防控制工作迫在眉睫。Objective To investigate the distribution characteristics and factors associated with syphilis-HIV co-infection among men who have sex with men（MSM）in Shenzhen city. Methods Syphilis/HIV surveillance data were collected among MSM from 2005 to 2011 in Shenzhen and analyzed with Cochran-Armitage trend test and logistic regression. Results A total of 5 232 MSM receiving voluntary counseling and testing were enrolled in the study.The infection rate of syphilis,HIV,and syphilis-HIV co-infection among the MSM was 20.97%,6.46%,and 3.56%,respectively.The positive rate of syphilis-HIV co-infection increased gradually from 2005 to 2011（Z=-3.7359,P=0.0002）.The results of multivariate logistic regression analysis showed that syphilis-HIV co-infection was significantly associated with age,education level and role in homosexual behavior.The relative risk of syphilis-HIV co-infection for the MSM aged greater than or equal to 40 years was 2.165（odds ratio [OR]=2.165）compared with those less than 40 years.The relative risk of syphilis-HIV co-infection for the MSM with high school education and college or above education was 0.714 and 0.522（OR=0.714 and OR=0.522）compared with those with junior school or below.The relative risk of syphilis-HIV co-infection for the MSM mainly with insertive anal sex and with both receptive and insertive anal sex was 0.388（OR=0.388）and 0.606（OR=0.606）compared with those mainly with receptive anal sex. Conclusion The prevalence rate of syphilis-HIV co-infection showed a statistically significant increase from 2005 to 2011 and it is urgent to control and prevent syphilis/HIV oc-infection among MSM in Shenzhen.

关 键 词：男男性行为者(MSM) 梅毒 人类免疫缺陷病毒(HIV) 

分 类 号：R512.91[医药卫生—内科学] R759[医药卫生—临床医学]