老年脑梗死患者记忆障碍影响因素分析  

Influencing factors of dysmnesia in elderly cerebral infarction patients

作　　者：陈长香[1] 郝英秀[1] 吴安娜[1] 郝习君[1] 李淑杏[1] 赵雅宁[1] 

机构地区：[1]河北联合大学护理与康复学院,河北唐山063000

出　　处：《中国公共卫生》2013年第8期1140-1143,共4页Chinese Journal of Public Health

基　　金：国家社会科学基金(12BRK017);河北省科技支撑项目(2009276103D-3)

摘　　要：目的了解老年脑梗死患者记忆障碍患病情况及影响因素,为采取干预措施提供依据。方法以2010年4月—2011年10月在河北联合大学附属医院神经内科住院的429例60～80岁老年脑梗死患者为研究对象,应用英国Rivermead康复中心设计的行为记忆测验第二版(RBMT-Ⅱ)对其进行记忆功能测试。结果脑梗死患者发生记忆障碍者为342例,占79.7%,其中轻度99例,占23.1%,中度187例,占43.6%,重度56例,占13.0%;单因素分析结果显示,高龄、女性、低学历及退休前从事体力劳动、患高血压、糖尿病和高血脂、复发者、脑梗死部位在颞叶、额叶、丘脑、基底节的老年脑梗死患者发生记忆障碍比例高,差异有统计学意义(P<0.01);多因素logistic回归分析结果显示,女性(OR=3.795)、患高血压(OR=2.261)、患糖尿病(OR=4.816)和复发(OR=1.919)是记忆障碍的危险因素;文化程度高(OR=0.429)和退休前从事脑力劳动(OR=0.120)是记忆障碍的保护因素;梗死部位在颞叶(OR=3.349)、额叶(OR=2.851)、丘脑(OR=4.940)和基底节(OR=4.414)时较其他部位更易发生记忆障碍。结论老年脑梗死患者记忆障碍的影响因素复杂,应引起重视。Objective To investigate the incidence and influential factors of dysmnesia in elderly patients with cerebral infarction and to provide evidence for intervention on the disease. Methods Totally 429（241 males,188 females）elderly hospitalized patients with cerebral infarction aged 60 to 80 years were recruited from neurology department of a hospital from April 2010 to October 2011.Rivermead Behavioural Memory Test（RBMT-Ⅱ）was adopted to assess memory function of the patients. Results In the patients,there were 342 diagosed as dysmnesia,with 99（23.1%） mild dysmnesia,187（43.6%） moderate dysmnesia,56（13.0%） serious dysmnesia,and a overall prevalent rate of 79.7%.Univariate analysis showed that old age,female,lower educational background,employment,hypertension,hyperlipemia and diabetes mellitus,relapse of the disease,and with infarction of temporal lobe,frontal lobe,thalamus or basal ganghia were significant risk factors for the incident of dysmnesia（P〈0.01 or P〈0.05）.Multivariate logistic regression analysis showed that risk factors for dysmnesia were female,hypertension,diabetes mellitus,and relapse of the infarction,and the protective factors were high educational background and with occupation of brainwork. Conclusion The influential factors of dysmnesia in elderly cerebral infarction patients are complex and more attentions should be paid to these factors.

关 键 词：脑梗死 记忆障碍 行为记忆测验第二版(RBMT-Ⅱ) 影响因素 

分 类 号：R181.37[医药卫生—流行病学]