西安地区37家医院2012年第2季度抗菌药物利用分析  

Analysis of the Application of Antimicrobial Drugs in 37 Hospitals from Xi’an Area during Second Quarter in 2012

作　　者：陈晟[1] 李琛 杨效宇[1] 张广江[1] 王惠川[1] 

机构地区：[1]西安市第四医院,西安710004 [2]西安市卫生局,西安710006

出　　处：《中国药房》2013年第30期2818-2821,共4页China Pharmacy

摘　　要：目的:了解西安地区医院抗菌药物的利用情况。方法:参照"2012年全国抗菌药物临床应用专项整治活动"中规定的抗菌药物合理应用指标,对西安地区37家医院2012年第2季度的抗菌药物合理应用指标和抗菌药物种类、销售金额、用药频度(DDDs)及日均费用(DDC)等进行回顾性分析。结果:该地区37家医院目前应用的抗菌药物品种都能控制在规定范围内,住院患者抗菌药物使用强度(AUD)指标达标率为41.67%,门诊患者抗菌药物处方比例指标达标率为45.94%,Ⅰ类切口手术预防用药率指标达标率为3.03%,Ⅰ类切口手术预防用药的品种选择、给药时机和疗程合理率指标达标率分别为48.48%、63.64%、36.36%,介入手术目前还不能完全做到不预防用抗菌药物,二级医院细菌病原学送检率较低。头孢菌素、喹诺酮类、广谱青霉素及其复方制剂的销售金额较多、DDDs较大。销售金额排序列前20位的药物中注射剂占95%;DDDs排序列前20位的药物中为口服常释剂型且DDC<50元的占65%。结论:该地区医院应继续加强住院患者抗菌药物AUD、门诊患者抗菌药物处方比例、Ⅰ类切口手术预防用药率、Ⅰ类切口手术预防用药疗程合理率、介入手术预防用药率、限制使用级和特殊使用级抗菌药物使用前微生物送检率等指标的控制;同时加强第3、4代头孢菌素和喹诺酮类药物的管理;继续保持在临床中以使用普通、主流的抗菌药品种和以口服给药为主的抗菌药物合理使用优势;在抗菌药物目录调整中注意对一些价格低廉、使用率高的品种进行保留,以促进该地区抗菌药物的进一步合理应用。OBJECTIVE：To investigate the application of antimicrobial drugs in the hospitals from Xi’an area.METHODS：By using retrospective method,the utilization of antimicrobial drugs in 37 hospitals during 2nd quarter in 2012 were analyzed statistically in terms of rational use index,types,consumption sum,DDDs and DDC,according to rational use index of antimicrobial drugs stated in National Clinical Use of Antimicrobial Drugs Special Rectification in 2012.RESULTS：The use of antimicrobial drugs in 37 hospitals was all in line with the limit standard;41.67% of inpatients AUD was up to the standard;45.94% of hospitals had ideal proportion of outpatient antimicrobial drugs;3.03% of hospitals had ideal prophylactic use of drugs in typeⅠincision;the qualification rate of type selection,medication timing and reasonable treatment course were 48.48%,63.64% and 36.36% in typeⅠincision,respectively;some interventional operation still needed to use antimicrobial drugs;delivered rate of secondary hospital was in low level.Cephalosporin,quinolone,broad spectrum penicillin and its compound preparations had great consumption sum and DDDs.Among top 20 antimicrobial drugs in the list of consumption sum,95% of them were injections;among top 20 drugs in the list of DDDs,65% were oral regular-release dosage form and DDC lower than 50 yuan.CONCLUSIONS：AUD,outpatient antibiotic usage rate,clean perioperative prophylaxis rate and its treatment period,interventional procedures prophylaxis rate and Pathogenic detection rate should be controlled more strictly in Xi’an area.The management of 3rd （4th） generation cephalosporins and quinolones should be strengthened;common and mainstream types of antimicrobial drugs and oral administration should be mostly adopted in the use of antimicrobial drugs.Cheap and frequently used antimicrobial drugs should be reserved in the antimicrobial drugs list,in order to further improve rational use of antimicrobial drugs in the area.

关 键 词：抗菌药物 销售金额 用药频度 分析 

分 类 号：R969.3[医药卫生—药理学] R287[医药卫生—药学]