不稳定型心绞痛患者血清N末端B型钠尿肽原检测的临床意义  

Clinical significance of the serum levels of NT-proBNP in patients with unstable angina pectoris

作　　者：乔亚京[1] 逯保军[1] 尹遇冬[1] 王娟[1] 

机构地区：[1]河南省焦作市人民医院心内科二区,454000

出　　处：《中国实用医刊》2013年第15期48-49,共2页Chinese Journal of Practical Medicine

摘　　要：目的探讨不稳定型心绞痛（UAP）患者检测血清N末端B型钠尿肽原（NT—proBNP）的临床意义。方法入选的120例UAP患者，所有患者均行冠状动脉造影检查，血清测定NT—proBNP和肌钙蛋白T（cTnT）水平。结果UAP患者血清NT—proBNP水平冠状动脉多支病变组高于单支、双支病变组（P〈0．05），双支病变组高于单支病变组（P〈0．05）；cTnT阳性组高于cTnT阴性组。结论NT—proBNP水平与冠脉病变程度呈正相关，有助于UAP患者疾病严重程度的判断，为临床诊疗提供依据。Objective To investigate the clinical significance of the serum levels of N-Terminal pro-Brin natriuretic pepetide （NT-proBNP） in patients with unstable angina pectoris. Methods One hundred and twenty patients with unstable angina pectoris were studied. All patients were performed with coronary artery angiography. The serum levels of NT-proBNP and cardiac troponin T （cTnT） were detec- ted. Results The NT-proBNP levels of multi-vessel disease group were significantly higher than the double-and single-vessel disease group （P 〈 0. 05） , and the double-vessel disease group was higher than the single-vessel disease group（ P 〈 0. 05 ） ;The NT-proBNP levels in the eTnT positive group were signifi- cantly higher than that of the negative group （ P 〈 0. 05 ）. Conclusions The increase of NT-proBNP lev- els is positively correlated with the severity of coronary artery involvement in patients with unstable angi- na, contribute to disease severity judgments, to provide basis for clinical diaunosis and therapy.

关 键 词：不稳定型心绞痛 N末端B型钠尿肽原 肌钙蛋白T 

分 类 号：R541.4[医药卫生—心血管疾病]