颈动脉斑块形成与脑梗死的临床研究  

Clinical Research and Cerebral Infarction with Carotid Artery Plaque Formation

作　　者：张权孝[1,2] 张建庆[1,2] 马蕾[1,2] 

机构地区：[1]大庆油田总医院集团龙南医院 [2]齐齐哈尔医学院附属第五医院,黑龙江大庆1634530

出　　处：《中国伤残医学》2013年第7期50-51,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：研究颈动脉粥样硬化斑块的特点与脑梗死的关系及其影响。方法：对65例新发生的脑梗死患者做颈动脉超声检查，观察动脉内膜中层厚度（IMT）、斑块的结构特点及管腔的狭窄程度，并与45例年龄相当、伴随疾病相似、无明显缺血性脑血管疾病症状、体征的患者进行对比。结果：（1）脑梗死组IMT与对照组IMT比较无明显显著差异（P〉0．05）。（2）脑梗死组软斑和溃疡斑的发生率高于对照组（P〈0．05）。（3）2组间管腔狭窄程度皆以轻度狭窄（〈50％）为主，但脑梗死组中度狭窄（50％-75％）及严重狭窄（〉75％）的比率高于对照组。结论：脑梗死组颈动脉粥样硬化斑块特点与对照组有明显不同，这些特点可能与发生脑梗死有较密切关系。Objective：The relationship between features and cerebral infarction and its effect on carotid atherosclerosis plaque. Meth- ods ： carotid ultrasound examination on the patients with cerebral infarction 65 cases happen, observe the intima - media thickness （IMT） , the degree of stenosis of the lumen of the structure characteristics and patches, and in 45 age - matched comparison, with no obvious signs of disease similarity, ischemic eerebrovascular disease symptoms, patients. Results： （ 1 ） IMT in cerebral infarction group compared with the control group IMT had no significant difference （ P 〉 0.05 ）. （ 2 ） cerebral infarction group soft plaque and ulcer plaque occurrence rate is higher than that of the control group （ P 〈 O. 05 ）. （ 3 ） between the two groups with mild stenosis degree of lumen stenosis （ 〈 50% ） , but the cerebral infarction group （ 50% ~75% ） and moderate stenosis, severe stenosis （ 〉 75% ） ratio is higher than that of the control group. Conclusion： cerebral infarction carotid plaques and the control group are significantly different, these characteristics may have a close relationship with the occurrence of cerebral infarction.

关 键 词：颈动脉斑块 脑梗死 临床研究 

分 类 号：R541.4[医药卫生—心血管疾病]