血液净化抢救毒蕈中毒的研究  

Study on the rescue of mushroom poisoning blood purification

作　　者：刘勇胜[1] 

机构地区：[1]云南省西双版纳州人民医院重症医学科,云南西双版纳666100

出　　处：《中国卫生产业》2013年第23期22-23,共2页China Health Industry

摘　　要：目的分析和探讨血液净化抢救毒蕈中毒的疗效。方法选取本院2009年1月—2012年1月期间抢救的25例毒蕈中毒患者为研究对象。根据患者的病情,进行常规抢救、血液灌流、解毒治疗等综合治疗,观察患者治疗前及治疗后2d、4d丙氨酸氨基转移酶(ALT)、血清肌酸激酶(CK)、尿素氮(BUN)、肌酸激酶CK同工酶MB(CK-MB)、天门冬氨酸氨基转移酶(AST)、血清总胆红素(TBIL)、活化部分凝血活酶时间(APTT),血肌酐(CR)、血氨(NH3)等指标的变化情况及尿量恢复情况。结果 25例患者中,23例治愈出院,1例并发脑出血放弃治疗,1例。最短住院天数为7d,最长住院天数为25d,平均16d。治疗后2d和4d患者血ALT、AST、TBIL、NH3、APTT较治疗前显著下降,P<0.05,提示有统计学意义。患者尿量恢复正常时间1～7d,尿量增加于治疗后3.8d出现,进入多尿期平均5.1d。结论血液净化抢救毒蕈中毒疗效较为理想,值得临床推广应用。Objective To analysis and discuss the clinical efficacy of blood purification treatment of mushroom poisoning. Methods The hospital in 2009 January--2012 January 25 cases of mushroom poisoning patients rescue period as the research object. According to the condition of patients, routine treatment, blood flow, comprehensive treatment of detoxification treatment, patients were observed before and after treatment 2D, 4D alanine aminotransferase （ALT）, serum creatine kinase （CK）, blood urea nitrogen （BUN）, creatine kinase isoenzyme CK MB （CK-MB）, aspartate aminotransferase enzyme （AST）, serum total bilirubin （TBIL）, activated partial thromboplastin time （APTT）, serum creatinine （CR）, blood ammonia （NH3） and the change of urine volume index of recovery. Results Among the 25 patients, 23 cases were cured, 1 cases of cerebral hemorrhage complicated with give up treatment, 1 cases. The shortest length of hospital stay was 7 d, the longest length of hospital stay was 25 d, the average 16 d. After treatment, blood of patients with 2 d and 4 d ALT, AST, TBIL, NH3, APTT compared with those before treatment decreased significantly, P〈0.05, there was statistical significance tips. Patients with normal urine output time 1-7 d, urine volume increased 3.8d after treatment, the average 5.1 d in diuresis stage. Conclusion The clinical efficacy of blood purification treatment of mushroom poisoning is ideal, it is worthy of clinical application.

关 键 词：血液净化 毒蕈 中毒 

分 类 号：R4[医药卫生—临床医学]