血液灌流治疗急性百草枯中毒  

Clinical analysis of hemoperfusion for acute paraquat poisoning

作　　者：孙林[1] 万珊[1] 夏敏[1] 艾伟[1] 高金全[1] 

机构地区：[1]崇州市人民医院,四川崇州611230

出　　处：《四川医学》2013年第5期585-586,共2页Sichuan Medical Journal

基　　金：四川省科技支持计划(项目编号:2012SZ0102);四川省卫生适宜推广项目(编号:12-38-1502463)

摘　　要：目的总结分析血液灌流联合大剂量甲泼尼龙、环磷酰胺冲击治疗急性百草枯中毒的临床疗效。方法将本院2011～2012年收治的急性百草枯中毒患者78例分为两组,未灌流组使用大剂量甲泼尼龙、环磷酰胺冲击治疗;灌流组在此基础上早期联合血液灌流治疗。结果灌流组百草枯尿液浓度下降趋势显著优于未灌流组,降低了病死率。结论血液灌流联合大剂量甲泼尼龙、环磷酰胺冲击治疗急性百草枯中毒可更快清除尚未侵入器官的百草枯毒素,降低其对重要器官的损害,提高临床救治成功率。Objective To analyze the clinical efficacy of hemoperfusion combined with high dose methylprednisolone and cyclophosphamide pulse therapy for acute paraquat（PQ） poisoning.Methods 78 cases in our hospital from 2012 to 2013 were divided into two groups.Non hemoperfusion group with high-dose methylprednisolone and cyclophosphamide pulse therapy,based on the therapy,hemoperfusion group combined hemoperfusion in the treatment of early.Results The paraquat urine concentration of hemoperfusion group decreased significantly than that of non hemoperfusion group,reducing the mortality rate.Conclusion Hemoperfusion combined with large dose of methylprednisolone,cyclophosphamide pulse therapy in the treatment of acute paraquat poisoning effect.

关 键 词：百草枯 中毒 血液灌流 甲强龙 

分 类 号：R595.4[医药卫生—内科学]