莫西沙星治疗37例老年卒中相关性肺炎的临床疗效分析  

Analysis of clinical efficacy of moxifloxacin in the treatment of 37 elderly patients with stroke associated pneumonia

作　　者：哈玲梅[1] 王宏鑫[1] 

机构地区：[1]武警后勤学院附属医院急诊科,天津300162

出　　处：《临床肺科杂志》2013年第9期1615-1616,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的分析并评价莫西沙星治疗老年卒中相关性肺炎的临床疗效及副作用。方法将我院收治的71例住院老年卒中相关性肺炎病人分为观察组与对照组,观察组37例病人静脉滴注400 mg的莫西沙星注射液;对照组34例静脉滴注1000mg的头孢他啶,一个疗程为7～10 d,对比分析两组的临床疗效及副作用。结果经治疗后,观察组37例病人治疗有效率为89.19%,对照组34例病人治疗有效率为73.53%,观察组明显高于对照组(χ2=4.163,P<0.05),两组比较差异存在统计学意义;观察组细菌清除率为93.33%,对照组清除率为73.33%,两组清除率相比差异显著(P<0.05)。结论应用莫西沙星治疗老年卒中相关性肺炎的疗效确切、安全,细菌清除率高。Objective To analyze and evaluate the clinical effect and side effect of moxifloxacin in the treatment of senile patients with stroke associated pneumonia. Methods 71 elderly patients with stroke associated pneumonia were randomly divided into the observa- tion group （ n = 37 ） and the control group （ n = 34 ）. The observation group was treated with 400mg of moxifloxacin intravenous infusion, and the control group was treated with 1000mg of intravenous infusion ceftazidime. One period of treatment was 7 - 10 days. The clinical efficacy and side effect were compared between the two groups. Results After the treatment, the effective rate was 89. 19% in the obser- vation group and 73.53% in the control group respectively （X^2 =4. 163, P 〈0. 05）. The rate of bacterial clearance was 93.33% in the observation group and 73.33% in the control group with significant difference （ X^2 =4. 191, P 〈 0. 05 ）. Conclusion The application of moxifloxacin in the treatment of senile patients with stroke associated pneumonia is safe and effective, with high bacterial clearance rate.

关 键 词：卒中相关性肺炎 莫西沙星 头孢他啶 临床疗效 

分 类 号：R563.1[医药卫生—呼吸系统]