血浆置换联合化疗治疗噬血细胞综合征五例疗效观察  

Effect of plasma exchange combined with chemotherapy in the treatment of 5 cases of hemophagocytic syndrome

作　　者：冯春锐[1] 蔡力生[1] 蔡云[1] 李明 杜新 卓家才[1] 

机构地区：[1]深圳市第二人民医院血液科,广东深圳518035 [2]深圳市血液病研究所,广东深圳518035

出　　处：《海南医学》2013年第15期2283-2284,共2页Hainan Medical Journal

摘　　要：目的观察血浆置换联合化疗治疗噬血细胞综合征的临床疗效。方法回顾性分析本院采用血浆置换联合化疗治疗5例噬血细胞综合征患者的临床资料。结果 5例患者中4例治疗后相关指标好转,生存期超过6个月,1例无效,2个月后死亡,平均生存期6.1个月。结论血浆置换联合化疗的方法对控制噬血细胞综合征的病情、延长患者的生存期有一定效果。Objective To evaluate the clinical efficacy of plasma exchange combined with chemotherapy in the treatment of hemophagocytic syndrome. Methods Five patients diagnosed with hemophagocytie syndrome and treated by plasma exchange combined with chemotherapy in our hospital were selected as the research objects. The clinical data was studied retrospectively. Results Of the 5 patients, 4 achieved improvements after treatment, with the survival time of over 6 months. One achieved no improvements and died in 2 months, with the mean survival time of 6.1 months. Conclusion Plasma exchange combined with chemotherapy can effectively control the progression of the disease and prolong survival in hemophagocytic syndrome.

关 键 词：噬血细胞综合征 血浆置换 化疗 治疗 

分 类 号：R442.8[医药卫生—诊断学]