数字减影CT灌注成像在股骨头早期缺血性坏死中的应用  

Application of subtraction CT perfusion imaging in early avascular necrosis of femoral head

作　　者：刘海明[1] 梁辉清[1] 刘万新[1] 刘日新[1] 黄锦钊[1] 袁国奇[1] 

机构地区：[1]广东医学院附属陈星海医院放射科,广东中山528415

出　　处：《海南医学》2013年第16期2396-2398,共3页Hainan Medical Journal

基　　金：广东省中山市科技计划项目(编号:20102A122)

摘　　要：目的探讨数字减影CT灌注成像(SubtractionCTperfusionimaging,SCTP)在股骨头早期缺血坏死(Avascularnecrosisoffemoralhead,ANFH)中的应用。方法股骨头早期缺血性坏死19例,股骨头灌注前先行平扫,再进行同层面灌注扫描,将灌注图像经数字减影后得到一组新灌注图像。再经工作站灌注软件后处理,计算出血流量(BF)、血容量(BV)、对比剂平均通过时间(MTT)及相应色阶图,用于ANFH诊断。结果早期ANFH患侧(27侧)股骨头BF数值较健侧(11侧)BF显著减少,差异有统计学意义(P<0.05)。患侧股骨头BV、MTT数值对比健侧组间差异无统计学意义(P>0.05)。结论 SCTP计算出的BF、BV、MTT能反映早期股骨头缺血的微循环灌注信息,可以为临床诊断ANFH提供重要的诊断依据。Objective To investigate the application of subtraction CT perfusion imaging （SCTP） in early avascular necrosis of femoral head （ANFH）.Methods Nineteen patients of ANFH were performed plain CT scan before the perfusion,and then performed perfusion scan at the same levels.The perfusion images were processed by digital subtraction perfusion software to get a group of new perfusion images.Then the images were post-processed by workstation perfusion software,and blood flow （BF）,blood volume （BV）,mean transit time （MTT） and the corresponding color mapping were calculated for the diagnosis of ANFH.Results The BF value of femoral head at the affected side of early ANFH （n=27） were significantly reduced,compared with that at the healthy side （n=11）,P＜0.05.There were no statistically significant differences in BV or MTT between the two sides （P＞0.05）.Conclusion BF,BV,MTT can demonstrate the microcirculation perfusion information of ANFH,which provides an important basis for the clinical diagnosis of ANFH.

关 键 词：灌注成像 数字减影 股骨头坏死 X线计算机体层摄影术 

分 类 号：R445[医药卫生—影像医学与核医学]