正常人尿样中总β放射性测量方法的研究  

Measurement of gross β activity in urine of normal adults

作　　者：王丽琴[1] 杨姗姗[2] 屈喜梅[1] 焦玲[1] 姜恩海[1] 武权[1] 张文艺[1] 

机构地区：[1]北京协和医学院中国医学科学院放射医学研究所天津市分子核医学重点实验室,天津300192 [2]天津市职业病防治院

出　　处：《中华放射医学与防护杂志》2013年第3期310-313,共4页Chinese Journal of Radiological Medicine and Protection

摘　　要：目的对正常成年人尿液中的总β放射性水平进行测量，建立一种适用于大批量样品放射性筛查的标准方法。方法采用蒸发浓缩法对83例正常成年人尿样进行样品预处理，并使用低本底测量仪器测量总β放射性水平。结果最佳实验条件为：样品量200ml，采用硝酸盐化处理，灰化条件300℃、2h，测量时间1000min，尿样残渣搁置24h后再测得到的结果更稳定；正常成年人尿样中放射性水平为9．40—52．92Bq／L，且与年龄、性别无关。结论使用该方法进行尿中总β放射性检测，制样方法简单且能满足大批量样品筛查的需求。Objective To measure the total β radioactive background level in the urine of normal adults, and to establish the method which can be universally used and satisfy the needs of rapid screening of samples in large batch. Methods A total of 83 urine samples from healthy adults were prepared by evaporation. And the gross β activity in urine was detected by using low background measuring instrument. Results The optimal experimental conditions were in place. The sampled volume was 200 ml, and the samples were turned to nitric acid salinization, ashed at 300℃ for 2 h, and the measured time was 1000 min. To get a more stable result, the urine residues were put aside for 24 h before measurement. The radioactivity in urine of healthy adults was between 9.40 -55.92 Bq/L, and showed no correlation with age and sex. Conclusions When the radioactivity in urine is detected under the conditions mentioned above, the sample preparation process is simple and quickly, which can satisfy the needs of large batch sample screening.

关 键 词：尿样 总Β放射性 放射性筛查 

分 类 号：R446[医药卫生—诊断学]