2型糖尿病患者胰腺的多排螺旋CT灌注研究  

Study on multisection helical CT perfusion imaging in pancreas of type 2 diabetic patients

作　　者：邢千超[1] 冯平勇[1] 程豪[1] 高志红[1] 柳青[1] 

机构地区：[1]河北医科大学第二医院影像科,河北石家庄050000

出　　处：《临床荟萃》2013年第8期861-863,F0002,共4页Clinical Focus

摘　　要：目的应用多排螺旋CT(MSCT)灌注扫描技术评价2型糖尿病患者与正常人胰腺组织的血流动力学特点,探讨其临床应用价值。方法使用GE Lightspeed 16排MSCT对30例2型糖尿病患者及30例非胰腺疾病患者行胰腺CT灌注检查,按是否患糖尿病分为患病组与正常组,分别测量两组胰腺不同部位组织的血流量(BF)、血容量(BV)、平均通过时间(MTT)和表面通透性(PS)的平均值,并进行统计学分析。结果患病组与正常组胰腺体部的BV值(13.41±3.69)ml/kg vs(16.43±5.14)ml/kg,其差异有统计学意义(P<0.05),而BF、MTT及PS值之间比较差异无统计学意义;胰头部及胰腺尾部各灌注参数间差异无统计学意义。结论 MSCT灌注成像对2型糖尿病患者胰腺组织的血流变化分析有一定的临床价值。Objective The study was to evaluate the pancreatic hemodynamic characteristics of type 2 diabetic patients and healthy people by multisection helical CT（MSCT） perfusion scanning technology,and explore the clinic value.Methods Pancreatic perfusion CT examination was performed in 30 cases with type 2 diabetic patients and 30 subjects without pancreatic diseases by using GE Lightspeed 16-slice MSCT.The subjects were divided into prevalence group group and normal group according to whether diabetes or not existed,and then,subjects were measured the mean blood flow（BF）,blood volume（BV）,mean transit time（MTT） and permeability surface（PS） in different parts of pancreas,and the data were analyzed statistically.Results The BV values of pancreatic body in prevalence group and normal group were（13.41±3.69） ml/kg and（16.43±5.14） ml/kg,the difference between the two groups was statistically significant（P0.05）,the BF,MTT and PS between the two groups showed no significant difference;The BF,BV,MTT and PS values showed no statistically significant between the pancreatic head and pancreatic tail in prevalence group and normal group.Conclusion The BF analysis of pancreas in type 2 diabetic patients has certain clinical value by using MSCT perfusion imaging.

关 键 词：糖尿病 2型 体层摄影术 螺旋计算机 胰腺 血流灌注 

分 类 号：R587.1[医药卫生—内分泌]