盐酸右美托咪定在机械通气患者的疗效观察  

The Effect of Dexmedetomidine in Mechanical Ventilated Patients

作　　者：谭家香[1] 周锦贤[1] 关阳东[1] 林熙泉[1] 

机构地区：[1]广东省开平市中心医院ICU室,广东开平529300

出　　处：《中国卫生产业》2013年第14期30-31,共2页China Health Industry

摘　　要：目的探讨盐酸右美托咪定在ICU机械通气患者的疗效观察。方法将患者随机分成两组:咪达唑仑组(A组)和盐酸右美托咪定组(B组),每组各45例,记录使用前的急性生理和慢性健康状态评分Ⅱ(APACHEⅡ)评分,Ramsay评分和PaO2/FiO2指标;记录镇静中3、6、9h的心率、血压和呼吸;镇静满意程度、恢复时间。结果患者使用盐酸右美托咪定镇静满意程度明显高于咪达唑仑组,恢复时间较咪达唑仑组短,差异有统计学意义(P<0.05)。结论对于机械通气患者的镇静,盐酸右美托咪定优于咪达唑仑。Objective To explore the sedative efficacity of dexmedetomidine on mechanical ventilated patients in intensive care unit. Methods Ninety patients were divided into midazolam group （group A）and dexmedetomidine group （group B）, with 45 patients in each group.Recorded the APACHE II score, Ramsay score and PaO2/FiO2 indicators before sedation. Heart rate, blood pressure and respiration were recorded at 3h, 6h and 9h after sedation, then recorded the sedation level, recovery time from mechanical ventilation. Results The sedation level of the dexmedetomidine group was was significantly higher than the midazolam group （P 〈 0.05）, the recovery time from mechanical ventilation of the dexmedetomidine group was significantly shorter than the midazolam group （P 〈 0.05）. Conclusion In sedation of mechanical ventilation patients, dexmedetomidine is better than midazolam.

关 键 词：盐酸右美托咪定 机械通气 镇静 咪达唑仑 

分 类 号：R614[医药卫生—麻醉学]